There is substantial evidence that oxidative stress participates in the pathophysiology of
cardiovascular disease. Biochemical, molecular and pharmacological studies further …

In addition to its critical role in purine metabolism, xanthine oxidoreductase (XOR) has been
implicated in the development of tissue oxidative damage in a wide variety of respiratory and …

Cardiovascular diseases (CVD) are the leading cause of global mortality and their
pathogenesis lies mainly in the atherosclerotic process. There are close connections linking …

Human xanthine oxidoreductase (XOR) is a multiple-level regulated enzyme, resulting from
a complicated evolutionary process that assigned it many physiological roles. The main …

Endothelial xanthine oxidoreductase (XOR) together with NAD (P) H oxidase and nitric
oxide (NO) synthase plays a physiologic role in inflammatory signalling, the regulation of NO …

Xanthine oxidoreductase (XOR) is a ubiquitous complex cytosolic molybdoflavoprotein
which controls the rate limiting step of purine catabolism by converting xanthine to uric acid …

Hemolytic diseases are associated with elevated levels of circulating free heme that can
mediate endothelial dysfunction directly via redox reactions with biomolecules or indirectly …

Xanthine oxidoreductase (XOR) is a ubiquitous metalloflavoprotein that appears in two
interconvertible yet functionally distinct forms: xanthine dehydrogenase (XD), which is …

Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome
through the oxidative stress and the inflammatory response induced by XOR-derived …

Xanthine oxidoreductase (XOR) is a complex molybdoflavoenzyme, present in milk and
many other tissues, which has been studied for over 100 years. While it is generally …