Clear delineation of tumor margins is essential for accurate resection and decreased
recurrence rate in the clinic. Fluorescence imaging is emerging as a promising alternative to …

Cancer, a leading cause of death worldwide, still needs surgery as essential curation in over
80% population. However, complete resection of cancerous tissues remains a great …

Accurate intraoperative tumor delineation is critical to achieving successful surgical
outcomes. However, conventional techniques typically suffer from poor specificity and low …

In cancer surgery, complete surgical resection of tumor lesions is critical to optimize the
outcome. However, it is sometimes difficult to distinguish the boundary between tumor and …

Surgical treatment is the most effective treatment for renal cancer. It is urgent to develop
highly selective and sensitive analytical methods for specially lighting up the kidney tumor …

Fluorescence (FL)-guided detection of cancer is one of the most promising approaches to
achieve intraoperative assessment of surgical margins. Enzymes, such as aminopeptidase …

The recurrence of malignant tumors is mostly caused by incompleted surgical resection.
Especially, it is difficult for surgeons to detect and accurately remove metastatic tumors by …

Malignant tumors are a severe threat to human health. Surgical removal is still the preferred
method in clinical practice among the many treatment strategies. Nevertheless, tiny residual …

Fluorescent probes that can selectively detect tumour lesions have great potential for
fluorescence imaging-guided surgery. Here, we established a library-based approach for …

The real-time, dynamic optical visualization of lesions and margins ensures not only
complete resection of the malignant tissues but also better preservation of the vital …