[HTML][HTML] Methods for in vitro evaluating antimicrobial activity: A review

M Balouiri, M Sadiki, SK Ibnsouda - Journal of pharmaceutical analysis, 2016 - Elsevier
In recent years, there has been a growing interest in researching and developing new
antimicrobial agents from various sources to combat microbial resistance. Therefore, a …

Next-generation antimicrobial susceptibility testing

A Van Belkum, WM Dunne Jr - Journal of clinical microbiology, 2013 - Am Soc Microbiol
Antimicrobial resistance has emerged as one of the most-significant health care problems of
the new millennium, and the clinical microbiology laboratory plays a central role in …

History and development of antimicrobial susceptibility testing methodology

PF Wheat - Journal of Antimicrobial Chemotherapy, 2001 - academic.oup.com
Antimicrobial susceptibility testing (AST) is performed daily on bacterial isolates in clinical
laboratories. The techniques employed are often taken for granted. This paper traces the …

Colorimetric microdilution assay: Validation of a standard method for determination of MIC, IC50%, and IC90% of antimicrobial compounds

A Veiga, TT Maria da Graça, LS Rossa… - Journal of …, 2019 - Elsevier
The emergence of multiresistant bacteria directly impacts on the search for new compounds
with antimicrobial activity, and it is important the improvement of new techniques are able to …

Preclinical evaluation of novel antibacterial agents by microbiological and molecular techniques

AJ O'Neill, I Chopra - Expert opinion on investigational drugs, 2004 - Taylor & Francis
The defining property of an antibacterial agent is its ability to selectively interfere with
bacterial growth and/or survival. Consequently, a considerable and crucial part of the …

Progress on the development of rapid methods for antimicrobial susceptibility testing

MR Pulido, M García-Quintanilla… - Journal of …, 2013 - academic.oup.com
Antimicrobial susceptibility testing is essential for guiding the treatment of many types of
bacterial infections, especially in the current context of rising rates of antibiotic resistance …

Tests for bactericidal effects of antimicrobial agents: technical performance and clinical relevance

LR Peterson, CJ Shanholtzer - Clinical microbiology reviews, 1992 - Am Soc Microbiol
Bactericidal testing has been used for several decades as a guide for antimicrobial therapy
of serious infections. Such testing is most frequently performed when bactericidal …

[HTML][HTML] Selection of appropriate analytical tools to determine the potency and bioactivity of antibiotics and antibiotic resistance

NA Dafale, UP Semwal, RK Rajput, GN Singh - Journal of pharmaceutical …, 2016 - Elsevier
Antibiotics are the chemotherapeutic agents that kill or inhibit the pathogenic
microorganisms. Resistance of microorganism to antibiotics is a growing problem around …

Comparison of the WST-8 colorimetric method and the CLSI broth microdilution method for susceptibility testing against drug-resistant bacteria

T Tsukatani, H Suenaga, M Shiga, K Noguchi… - Journal of …, 2012 - Elsevier
The minimum inhibitory concentrations (MICs) obtained from the susceptibility testing of
various bacteria to antibiotics were determined by a colorimetric microbial viability assay …

Identification and antibiotic‐susceptibility profiling of infectious bacterial agents: a review of current and future trends

G Maugeri, I Lychko, R Sobral… - Biotechnology …, 2019 - Wiley Online Library
Antimicrobial resistance is one of the most worrying threats to humankind with extremely
high healthcare costs associated. The current technologies used in clinical microbiology to …