Postoperative cognitive dysfunction, confusion, and delirium are common after general
anesthesia in the elderly, with symptoms persisting for months or years in some patients …

Abnormal hyperphosphorylation and aggregation of microtubule-associated protein tau play
a crucial role in neurodegeneration of Alzheimer's disease (AD). Anesthesia has been …

Alzheimer's disease and other tauopathies are characterized by the presence of intracellular
neurofibrillary tangles composed of hyperphosphorylated, insoluble tau. General anesthesia …

In Alzheimer's disease (AD) and other tauopathies, the microtubule-associated protein tau
can undergo aberrant hyperphosphorylation potentially leading to the development of …

Alzheimer's disease (AD) is the most common form of dementia and remains a growing
worldwide health problem. As life expectancy continues to increase, the number of AD …

Anesthetic isoflurane has been shown to promote Alzheimer's disease (AD)
neuropathogenesis by inducing caspase activation and accumulation of β-amyloid (Aβ) …

In this review, we aim to provide clinical insights into the relationship between surgery,
general anesthesia (GA), and dementia, particularly Alzheimer's disease (AD). The …

Background There is a growing interest in the involvement of anesthetic agents in the
etiology of postoperative cognitive dysfunction. Recent animal studies suggest that acute …

The incidence of Alzheimer's disease (AD) in individuals> 65 years of age is 13% and~ 66
million individuals in this age group undergo surgery annually under anesthesia. It is …

Alzheimer's disease (AD), an insidious and progressive neurodegenerative disorder
accounting for the vast majority of dementia, is characterized by global cognitive decline and …