Inhibitory effects of the nanoscale lysate derived from xenogenic dental pulp stem cells in lung cancer models

Y He, R Li, W She, Y Ai, K Li, T Kumeria, Z Jiang… - Journal of …, 2023 - Springer
Background Lung cancer is a highly prevalent malignancy and has the highest mortality rate
among all tumors due to lymph node metastasis. Bone marrow and umbilical cord-derived …

Effect of human Wharton's jelly mesenchymal stem cell secretome on proliferation, apoptosis and drug resistance of lung cancer cells

F Hendijani, SH Javanmard, L Rafiee… - Research in …, 2015 - journals.lww.com
Multipotent mesenchymal stem cells (MSCs) are recently found to alter the tumor condition.
However their exact role in tumor development is not yet fully unraveled. MSCs were …

[HTML][HTML] Secretome of dental pulp-derived stem cells reduces inflammation and proliferation of glioblastoma cells by deactivating Mapk-Akt pathway

P Prateeksha, MSI Howlader, S Hansda… - Diseases & …, 2023 - ncbi.nlm.nih.gov
Background: Dental pulp-derived stem cells (DPSC) is a promising therapy as they
modulate the immune response, so we evaluated the inhibitory effect of DPSC secretome …

Dental pulp stem cells (DPSCs) increase prostate cancer cell proliferation and migration under in vitro conditions

A Doğan, S Demirci, H Apdik, EA Apdik, F Şahin - Tissue and Cell, 2017 - Elsevier
Cancer as a multistep and complicated disease is regulated by several molecular and
cellular events. Cancer treatment could be managed at the early stages when the tumor is …

[HTML][HTML] Assessing the effect of human dental pulp mesenchymal stem cell secretome on human oral, breast, and melanoma cancer cell lines

AT Raj, S Kheur, R Bhonde, VR Mani… - Saudi Journal of …, 2021 - Elsevier
Background The secretome of the dental pulp mesenchymal stem cells (DPMSCS-S) have
an array of regenerative potential and could aid in the rehabilitation of cancer patients post …

Dental pulp stem cells used to deliver the anticancer drug paclitaxel

H Salehi, S Al-Arag, E Middendorp, C Gergely… - Stem cell research & …, 2018 - Springer
Background Understanding stem cell behavior as a delivery tool in cancer therapy is
essential for evaluating their future clinical potential. Previous in-vivo studies proved the use …

The growth factors and cytokines of dental pulp mesenchymal stem cell secretome may potentially aid in oral cancer proliferation

AT Raj, S Kheur, Z Khurshid, ME Sayed, MH Mugri… - Molecules, 2021 - mdpi.com
Background: Growth factors and cytokines responsible for the regenerative potential of the
dental pulp mesenchymal stem cell secretome (DPMSC-S) are implicated in oral …

[HTML][HTML] Suppressive effects of dental pulp stem cells and its conditioned medium on development and migration of colorectal cancer cells through MAPKinase …

E Nikkhah, F Kalalinia, MA Rezaee… - Iranian Journal of …, 2021 - ncbi.nlm.nih.gov
Objective (s): Mesenchymal stem cells (MSCs) extensively interact with cancer cells and
other stromal cells in the tumor microenvironment. However, the role of MSCs in colorectal …

A study on the effect of human dental pulp stem cell conditioned medium on human oral squamous cell carcinoma cell lines

S Hanyu, K Sakuma, A Tanaka - Journal of Hard Tissue Biology, 2019 - jstage.jst.go.jp
In recent years, the application of conditioned medium (CM) in regenerative medicine has
received much attention. However, the incidence of cancer in Japan is continuing to rise …

Safety and homing of human dental pulp stromal cells in head and neck cancer

G Merckx, M Lo Monaco, I Lambrichts… - Stem Cell Reviews and …, 2021 - Springer
Background Head and neck cancer (HNC) is one of the most common cancers, associated
with a huge mortality and morbidity. In order to improve patient outcomes, more efficient and …