Solid organ transplantation has become a mainstay in the contemporary management of
end-stage organ failures fueled by advances in immunosuppression, intensive care and …

Objectives: To review all published clinical studies of thyroid hormone administration to
brain-dead potential organ donors. Methods: A search of PubMed using multiple search …

Background Brain death frequently induces hemodynamic instability and cardiac stunning.
Impairments in cardiac performance are major contributors to hearts from otherwise eligible …

The aggressive management of brain‐dead (cadaveric) organ donors has been shown to
increase organs available for transplantation. Some centers use hormone therapy with …

Background Hormonal therapy to the brain-dead potential organ donor can include thyroid
hormone (triiodothyronine [T 3] or levothyroxine [T 4]), corticosteroids, antidiuretic hormone …

Background Hemodynamic instability and myocardial dysfunction are major factors
preventing the transplantation of hearts from organ donors after brain death. Intravenous …

Rationale Brain‐dead (BD) organ donors frequently exhibit hemodynamic instability and/or
reversible cardiac dysfunction. Retrospective studies have suggested that thyroid hormone …

Background Acute hypothyroidism after brain death results in hemodynamic impairments
that limit availability of donor hearts. Thyroid hormone infusions can halt that process and …

BACKGROUND Organ shortage is an ongoing problem in the United States. Most donor
organs are procured following brain death and a significant portion of brain-dead donors …

Introduction During brain death, several events occur, including hormonal. metabolic and
systemic changes. This systematic review aims to find the role of hormone therapy in …