Hyperoside alleviates postmenopausal osteoporosis via regulating miR‐19a‐5p/IL‐17A axis
H An, C Chu, Z Zhang, Y Zhang, R Wei… - American Journal of …, 2023 - Wiley Online Library
Problem Postmenopausal osteoporosis (PMO) is a common osteoporosis. Hyperoside
(Hyp), a natural flavonoid compound, has anti‐osteoporotic effects, but the underlying …
(Hyp), a natural flavonoid compound, has anti‐osteoporotic effects, but the underlying …
[HTML][HTML] MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12
WS Lian, JY Ko, YS Chen, HJ Ke, CK Hsieh… - Cell death & …, 2019 - nature.com
Osteoporosis deteriorates bone mass and biomechanical strength, becoming a life-
threatening cause to the elderly. MicroRNA is known to regulate tissue remodeling; …
threatening cause to the elderly. MicroRNA is known to regulate tissue remodeling; …
[HTML][HTML] Focusing on OB-OC-MΦ axis and miR-23a to explore the pathogenesis and treatment strategy of osteoporosis
TL Ma, P Zhu, ZR Ke, JX Chen, YH Hu… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis is a bone metabolic disorder characterized by decreased bone density and
deteriorated microstructure, which increases the risk of fractures. The imbalance between …
deteriorated microstructure, which increases the risk of fractures. The imbalance between …
[HTML][HTML] MicroRNA-19b-3p promotes cell proliferation and osteogenic differentiation of BMSCs by interacting with lncRNA H19
G Xiaoling, L Shuaibin, L Kailu - BMC medical genetics, 2020 - Springer
Background To investigated the role of miR-19b-3p in regulating bone marrow
mesenchymal stem cell (BMSC) proliferation and osteoblast differentiation. Methods The …
mesenchymal stem cell (BMSC) proliferation and osteoblast differentiation. Methods The …
MiR-151a-3p promotes postmenopausal osteoporosis by targeting SOCS5 and activating JAK2/STAT3 signaling
Y Fu, Y Xu, S Chen, Y Ouyang, G Sun - Rejuvenation Research, 2020 - liebertpub.com
Postmenopausal osteoporosis, the most common type of primary osteoporosis, poses a
significant threat to women's health worldwide. However, detailed molecular mechanism …
significant threat to women's health worldwide. However, detailed molecular mechanism …
[HTML][HTML] Aberrant expression of miR-33a-3p/IGF2 in postmenopausal osteoporosis patients and its role and mechanism in osteoporosis
C Wang, J Shen, W Zhang, X Wang, X Xu, X Lu… - Journal of Orthopaedic …, 2023 - Springer
Background Postmenopausal osteoporosis (PMOP), the most frequent bone-related
disease, is characterized by bone loss and fragile fractures, which is related to low bone …
disease, is characterized by bone loss and fragile fractures, which is related to low bone …
[HTML][HTML] Interleukin 17A: a Janus-faced regulator of osteoporosis
JM Scheffler, L Grahnemo, C Engdahl, C Drevinge… - Scientific reports, 2020 - nature.com
Abstract Interleukin (IL)-17A is a well-described mediator of bone resorption in inflammatory
diseases, and postmenopausal osteoporosis is associated with increased serum levels of IL …
diseases, and postmenopausal osteoporosis is associated with increased serum levels of IL …
[HTML][HTML] Osteoblast Hypoxia-Inducible Factor-1α Pathway Activation Restrains Osteoclastogenesis via the Interleukin-33-MicroRNA-34a-Notch1 Pathway
H Kang, K Yang, L Xiao, L Guo, C Guo, Y Yan… - Frontiers in …, 2017 - frontiersin.org
Functional cross-talk between osteoblasts and osteoclasts is a key process for bone
homeostasis. Although osteoblast hypoxia-inducible factor-1α (HIF-1α) pathway activation …
homeostasis. Although osteoblast hypoxia-inducible factor-1α (HIF-1α) pathway activation …
[HTML][HTML] Substance P blocks ovariectomy-induced bone loss by modulating inflammation and potentiating stem cell function
J Piao, JS Park, DY Hwang, Y Son, HS Hong - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Osteoporosis is an age-related disease caused by imbalanced bone remodeling resulting
from excessive bone resorption. Osteoporosis is tightly linked with induction of chronic …
from excessive bone resorption. Osteoporosis is tightly linked with induction of chronic …
[HTML][HTML] miR-128 plays a critical role in murine osteoclastogenesis and estrogen deficiency-induced bone loss
Postmenopausal osteoporosis (PMOP) is a severe health issue faced by postmenopausal
women. microRNA-128 (miR-128) is associated with aging, inflammatory signaling, and …
women. microRNA-128 (miR-128) is associated with aging, inflammatory signaling, and …