The incorporation of unnatural amino acids into proteins through genetic code expansion
has been successfully adapted to African claw-toed frog embryos. Six unique unnatural …

Site-specific incorporation of unnatural amino acids into proteins provides a powerful tool to
study protein function. Here we report genetic code expansion in zebrafish embryos and its …

Precise temporally regulated protein function directs the highly complex processes that
make up embryo development. The zebrafish embryo is an excellent model organism to …

Expanding the genetic code to enable the incorporation of unnatural amino acids into
proteins in biological systems provides a powerful tool for studying protein structure and …

Genetic code expansion allows unnatural (non-canonical) amino acid incorporation into
proteins of interest by repurposing the cellular translation machinery. The development of …

Expanding the Genetic Code of an Animal | Journal of the American Chemical Society ACS ACS
Publications C&EN CAS Find my institution Log In Journal of the American Chemical Society …

Site-specific incorporation of unnatural amino acids (UAAs) has greatly expanded the toolkit
available to study biological phenomena in single cells. However, to address questions …

Genetic code expansion is one of the most powerful technologies in protein engineering. In
addition to the 20 canonical amino acids, the expanded genetic code is supplemented by …

Genetic code expansion for unnatural amino acid mutagenesis has, until recently, been
limited to cell culture. We demonstrate the site-specific incorporation of unnatural amino …

The genetic code can be expanded to include unnatural amino acids (Uaas) by engineering
orthogonal components involved in protein translation. To be compatible with live cells, side …