Molecular biology of atherosclerosis

PN Hopkins - Physiological reviews, 2013 - journals.physiology.org
At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

Atherosclerosis pathophysiology and the role of novel risk factors: a clinicobiochemical perspective

V Mallika, B Goswami, M Rajappa - Angiology, 2007 - journals.sagepub.com
Atherosclerosis is the root cause of the biggest killer of the 21st century. Mechanisms
contributing to atherogenesis are multiple and complex. A number of theories—including the …

[图书][B] Atherosclerosis: molecular and cellular mechanisms

SJ George, J Johnson - 2010 - books.google.com
With atherosclerosis being the number one cause of death in the western world, this
handbook and ready reference provides a comprehensive account of the different stages …

Gene expression phenotypes of atherosclerosis

D Seo, T Wang, H Dressman, EE Herderick… - … , and vascular biology, 2004 - Am Heart Assoc
Objective—Fulfilling the promise of personalized medicine by developing individualized
diagnostic and therapeutic strategies for atherosclerosis will depend on a detailed …

Atherosclerosis: successes, surprises, and future challenges

P Libby, KE Bornfeldt, AR Tall - Circulation research, 2016 - Am Heart Assoc
532 Circulation Research February 19, 2016 unresolved questions and to exploit the newer
discoveries that have opened unanticipated horizons of understanding and raised novel …

Vascular biology of atherosclerosis: overview and state of the art

P Libby - The American journal of cardiology, 2003 - Elsevier
Our current understanding of the vascular biology of atherogenesis and its clinical
manifestations suggests a pathophysiology that is much more complex than mere lipid …

Molecular and cellular concepts in atherosclerosis

M Sanders - Pharmacology & therapeutics, 1994 - Elsevier
Atherosclerosis is a complex disease of uncertain cause. Its pathobiology is believed to
represent an abnormal expression of the processes of vascular healing. Etiologic models …

The biology of atherosclerosis comes full circle: lessons for conquering cardiovascular disease

P Libby - Nature Reviews Cardiology, 2021 - nature.com
Atherosclerosis causes myocardial infarction, ischaemic cardiomyopathy, many ischaemic
strokes and jeopardized limbs. Despite enormous progress, atherosclerosis has become the …

Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease

W Frąk, A Wojtasińska, W Lisińska, E Młynarska… - Biomedicines, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are disorders associated with the heart and circulatory
system. Atherosclerosis is its major underlying cause. CVDs are chronic and can remain …

Atherosclerosis: orchestrating cells and biomolecules involved in its activation and inhibition

A Munjal, R Khandia - Advances in protein chemistry and structural biology, 2020 - Elsevier
The term atherosclerosis refers to the condition of deposition of lipids and other substances
in and on the artery walls, called as plaque that restricts the normal blood flow. The plaque …