Objective There is growing evidence that adding non-steroidal anti-inflammatory drugs to
some psychopharmacological treatments may help to improve symptoms in patients …

Background Numerous studies have reported that inflammation is closely associated with
depression, and adjunctive non-steroidal anti-inflammatory drug (NSAID) treatment has …

Background: The pathophysiology of depression is associated with the hyperactivity of
immune inflammatory responses. Cyclooxygenase‐2 inhibitors such as celecoxib reduce …

Objective The aim of this research was to perform a systematic review to identify all
randomized controlled trials (RCTs) evaluating the efficacy and safety of add‐on celecoxib …

BACKGROUND Anti-inflammation drugs were uncovered to be a potential therapy for
depression. Celecoxib as a selective COX2 inhibitor is also one anti-inflammation drugs …

BACKGROUND: It has been proposed that the mechanism of the antidepressant effect of
celecoxib is linked to its anti-inflammatory action and particularly its inhibitory effect on pro …

The effects of celecoxib on a broad spectrum of mood disorders and on inflammatory
parameters have not yet been comprehensively evaluated. The aim of this study was to …

Signs of an inflammatory process, in particular increased pro-inflammatory cytokines and
increased levels of prostaglandine E 2 (PGE 2), have repeatedly been described in major …

Prolonged stress has been associated with elevated levels of circulating proinflammatory
cytokines. Cyclo-oxygenase-2 inhibitors such as celecoxib exert anti-inflammatory effects …

Given the role of low-grade inflammation in the pathophysiology of major depressive
disorder (MDD), anti-inflammatory strategies may improve treatment outcomes in some …