An outer membrane protein YiaD contributes to adaptive resistance of meropenem in Acinetobacter baumannii
L Han, Y Gao, Y Liu, S Yao, S Zhong… - Microbiology …, 2022 - Am Soc Microbiol
Acinetobacter baumannii is an important nosocomial pathogen that can develop various
resistance mechanisms to many antibiotics. However, little is known about how it evolves …
resistance mechanisms to many antibiotics. However, little is known about how it evolves …
Exposure to imipenem at sub-minimum inhibitory concentration leads to altered expression of major outer membrane proteins in Acinetobacter baumannii
Aims Acinetobacter baumannii is a nosocomial pathogen known to be multidrug-resistant
(MDR), especially to drugs of the carbapenem class. Several factors contribute to resistance …
(MDR), especially to drugs of the carbapenem class. Several factors contribute to resistance …
Peptidoglycan recycling promotes outer membrane integrity and carbapenem tolerance in Acinetobacter baumannii
ABSTRACT β-Lactam antibiotics exploit the essentiality of the bacterial cell envelope by
perturbing the peptidoglycan layer, typically resulting in rapid lysis and death. Many Gram …
perturbing the peptidoglycan layer, typically resulting in rapid lysis and death. Many Gram …
Overproduction of efflux pumps caused reduced susceptibility to carbapenem under consecutive imipenem-selected stress in Acinetobacter baumannii
Y Zhang, Z Li, X He, F Ding, W Wu, Y Luo… - Infection and Drug …, 2018 - Taylor & Francis
Purpose Acinetobacter baumannii is an important pathogen in the nosocomial infections
worldwide. Combining with carbapenemases, efflux pumps and outer membrane proteins …
worldwide. Combining with carbapenemases, efflux pumps and outer membrane proteins …
Role of OmpA in the multidrug resistance phenotype of Acinetobacter baumannii
Acinetobacter baumannii has emerged as a nosocomial pathogen with an increased
prevalence of multidrug-resistant strains. The role of the outer membrane protein A (OmpA) …
prevalence of multidrug-resistant strains. The role of the outer membrane protein A (OmpA) …
Meropenem selection induced overproduction of the intrinsic carbapenemase as well as phenotype divergence in Acinetobacter baumannii
X Chen, X Meng, Q Gao, G Zhang, H Gu… - International journal of …, 2017 - Elsevier
Acinetobacter baumannii 37662 is a carbapenem-susceptible isolate with bla OXA-51-like
as the sole carbapenemase gene. Following selection with meropenem (MEM) at a …
as the sole carbapenemase gene. Following selection with meropenem (MEM) at a …
[HTML][HTML] Increased ompW and ompA expression and higher virulence of Acinetobacter baumannii persister cells
BL Schmitt, BF Leal, M Leyser, MP de Barros… - BMC microbiology, 2023 - Springer
Background Acinetobacter baumannii is one of the main causes of healthcare-associated
infections that threaten public health, and carbapenems, such as meropenem, have been a …
infections that threaten public health, and carbapenems, such as meropenem, have been a …
[HTML][HTML] Transcriptome profiling in imipenem-selected Acinetobacter baumannii
KC Chang, HY Kuo, CY Tang, CW Chang, CW Lu… - BMC genomics, 2014 - Springer
Abstract Background Carbapenem-resistance in Acinetobacter baumannii has gradually
become a global challenge. To identify the genes involved in carbapenem resistance in A …
become a global challenge. To identify the genes involved in carbapenem resistance in A …
Mutation of CarO participates in drug resistance in imipenem‐resistant Acinetobacter baumannii
LJ Zhu, XY Chen, PF Hou - Journal of clinical laboratory …, 2019 - Wiley Online Library
Objective Acinetobacter baumannii has become an important problem because of the high
drug resistance rate. The aim of this study was to assess the antimicrobial resistance profile …
drug resistance rate. The aim of this study was to assess the antimicrobial resistance profile …
Outer membrane protein A contributes to antimicrobial resistance of Acinetobacter baumannii through the OmpA-like domain
HI Kwon, S Kim, MH Oh, SH Na, YJ Kim… - Journal of …, 2017 - academic.oup.com
Objectives Acinetobacter baumannii outer membrane protein A (AbOmpA) is involved in
bacterial pathogenesis. However, the role of AbOmpA in the antimicrobial resistance of A …
bacterial pathogenesis. However, the role of AbOmpA in the antimicrobial resistance of A …
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