Anticancer activity of a novel naringin‒dextrin nanoformula: Preparation, characterization, and in vitro induction of apoptosis in human hepatocellular carcinoma cells …

EE Mohamed, A Abdel-Moneim, OM Ahmed… - Journal of Drug Delivery …, 2022 - Elsevier
Dextrin is a polysaccharide but is small and of low complexity. Naringin is a flavonoid widely
known for its pharmacological properties. This study aimed to create a naringin–dextrin …

[HTML][HTML] Protective Effects of Naringin–Dextrin Nanoformula against Chemically Induced Hepatocellular Carcinoma in Wistar Rats: Roles of Oxidative Stress …

EE Mohamed, OM Ahmed, A Abdel-Moneim… - Pharmaceuticals, 2022 - mdpi.com
Nanotechnology holds great promise for the development of treatments for deadly human
diseases, such as hepatocellular carcinoma (HCC). In the current study, we compared the …

[HTML][HTML] Formulation design, statistical optimization, and in vitro evaluation of a naringenin nanoemulsion to enhance apoptotic activity in A549 lung cancer cells

S Md, NA Alhakamy, HM Aldawsari, M Husain, S Kotta… - Pharmaceuticals, 2020 - mdpi.com
Naringenin (NAR), a flavonoid mainly found in citrus and grapefruits, has proven anti-cancer
activities. However, the poor water solubility and low bioavailability of NAR limits its use as a …

[HTML][HTML] Shufeng Jiedu Capsule and its active ingredients induce apoptosis, inhibit migration and invasion, and enhances doxorubicin therapeutic efficacy in …

J Xia, L Rong, T Sawakami, Y Inagaki, P Song… - Biomedicine & …, 2018 - Elsevier
Abstract Background Shufeng Jiedu Capsule (SFJDC), a traditional Chinese medicine, has
been used widely as antiviral, antibacterial, antitumor, and anti-inflammatory drugs. Previous …

Sonication tailored enhance cytotoxicity of naringenin nanoparticle in pancreatic cancer: design, optimization, and in vitro studies

MH Akhter, S Kumar, S Nomani - Drug development and industrial …, 2020 - Taylor & Francis
Objective: In vitro, optimization, characterization, and cytotoxic studies of NAR nanoparticles
(NPs) to against pancreatic cancer. Method: The sonication tailored Naringenin (NARG) …

[HTML][HTML] Naringin–Dextrin Nanocomposite Abates Diethylnitrosamine/Acetylaminofluorene-Induced Lung Carcinogenesis by Modulating Oxidative Stress …

EE Mohamed, OM Ahmed, KMA Zoheir… - Cancers, 2023 - mdpi.com
Simple Summary Despite advancements in the field, lung malignancies are the primary
cause of cancer-attributable morbidity and mortality on a global scale. Recently, therapeutic …

Enhanced anticancer activity of naringenin-loaded nanoparticles in human cervical (HeLa) cancer cells

N Krishnakumar, N Sulfikkarali… - … & preventive nutrition, 2011 - Elsevier
Naringenin (NAR) is a naturally occurring plant bioflavonoid present in citrus fruits and
possesses a wide range of biological application including anticancer effects. However, its …

[HTML][HTML] Rumex dentatus inhibits cell proliferation, arrests cell cycle, and induces apoptosis in MDA-MB-231 cells through suppression of the NF-κB pathway

R Batool, E Aziz, BKH Tan, T Mahmood - Frontiers in pharmacology, 2017 - frontiersin.org
Background: Rumex dentatus, commonly known as tooth docked, is widely used in
traditional system of medicines. Although it is well reported for its biological activities and …

[HTML][HTML] Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest

MS Ahamad, S Siddiqui, A Jafri, S Ahmad, M Afzal… - PloS one, 2014 - journals.plos.org
A natural predominant flavanone naringenin, especially abundant in citrus fruits, has a wide
range of pharmacological activities. The search for antiproliferative agents that reduce skin …

[HTML][HTML] Activation of caspases and inhibition of ribosome biogenesis mediate antitumor activity of Chijongdan in A549 non-small lung cancer cells

BG Kim, HY Kwon, EJ Sohn, S Hwang… - … and alternative medicine, 2014 - Springer
Background Though herbal medicines have been used for cancer prevention and treatment,
their scientific evidences still remain unclear so far. Thus, complementary and alternative …