Mechanisms linking inflammation to insulin resistance

L Chen, R Chen, H Wang… - International journal of …, 2015 - Wiley Online Library
Obesity is now widespread around the world. Obesity‐associated chronic low‐grade
inflammation is responsible for the decrease of insulin sensitivity, which makes obesity a …

[HTML][HTML] Inflammation and insulin resistance

C De Luca, JM Olefsky - FEBS letters, 2008 - Elsevier
Obesity-induced chronic inflammation is a key component in the pathogenesis of insulin
resistance and the Metabolic syndrome. In this review, we focus on the interconnection …

Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction

H Khodabandehloo, S Gorgani-Firuzjaee… - Translational …, 2016 - Elsevier
Obesity is a major public health problem worldwide, and it is associated with an increased
risk of developing type 2 diabetes. It is now commonly accepted that chronic inflammation …

Cellular inflammatory responses: novel insights for obesity and insulin resistance

H Chen - Pharmacological Research, 2006 - Elsevier
Type 2 diabetes is rapidly becoming a worldwide epidemic. Obesity and sedentary lifestyle
are the main environmental causes for the development of insulin resistance and type 2 …

Inflammatory mechanisms in the regulation of insulin resistance

H Tilg, AR Moschen - Molecular medicine, 2008 - Springer
Insulin resistance (IR) plays a key role in the pathophysiology of obesity-related diseases
such as type 2 diabetes and nonalcoholic fatty liver disease. It has been demonstrated that …

Latent inflammation and insulin resistance in adipose tissue

IS Stafeev, AV Vorotnikov, EI Ratner… - International journal …, 2017 - Wiley Online Library
Obesity is a growing problem in modern society and medicine. It closely associates with
metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and …

Inflammation, cytokines and insulin resistance: a clinical perspective

V Wieser, AR Moschen, H Tilg - Archivum immunologiae et therapiae …, 2013 - Springer
Obesity and obesity-related disorders have dramatically increased globally in the last
decades. These entities are commonly associated with a state of insulin resistance and the …

Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?

K Rehman, MSH Akash - Journal of biomedical science, 2016 - Springer
Background Insulin resistance (IR) is one of the major hallmark for pathogenesis and
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …

Molecular targets related to inflammation and insulin resistance and potential interventions

SM Hirabara, R Gorjao, MA Vinolo… - BioMed Research …, 2012 - Wiley Online Library
Inflammation and insulin resistance are common in several chronic diseases, such as
obesity, type 2 diabetes mellitus, metabolic syndrome, cancer, and cardiovascular diseases …

Adipose tissue inflammation: a cause or consequence of obesity-related insulin resistance?

M Blüher - Clinical science, 2016 - portlandpress.com
The worldwide obesity epidemic has become a major health concern, because it contributes
to higher mortality due to an increased risk for noncommunicable diseases including …