n− 3 Polyunsaturated fatty acids exert immunomodulatory effects on lymphocytes by targeting plasma membrane molecular organization
SR Shaikh, CA Jolly, RS Chapkin - Molecular aspects of medicine, 2012 - Elsevier
Fish oil, enriched in bioactive n− 3 polyunsaturated fatty acids (PUFA), has therapeutic value
for the treatment of inflammation-associated disorders. The effects of n− 3 PUFAs are …
for the treatment of inflammation-associated disorders. The effects of n− 3 PUFAs are …
Regulatory activity of polyunsaturated fatty acids in T-cell signaling
n− 3 Polyunsaturated fatty acids (PUFA) are considered to be authentic immunosuppressors
and appear to exert beneficial effects with respect to certain immune-mediated diseases. In …
and appear to exert beneficial effects with respect to certain immune-mediated diseases. In …
Immunomodulation by polyunsaturated fatty acids: mechanisms and effects
TM Stulnig - International archives of allergy and immunology, 2003 - karger.com
Polyunsaturated fatty acids (PUFAs) modulate immune responses, thereby exerting
beneficial effects in a variety of inflammatory disorders. PUFAs of the n-3 series that are …
beneficial effects in a variety of inflammatory disorders. PUFAs of the n-3 series that are …
N-3 polyunsaturated fatty acids modulate B cell activity in pre-clinical models: Implications for the immune response to infections
J Whelan, KM Gowdy, SR Shaikh - European journal of pharmacology, 2016 - Elsevier
B cell antigen presentation, cytokine production, and antibody production are targets of
pharmacological intervention in inflammatory and infectious diseases. Here we review …
pharmacological intervention in inflammatory and infectious diseases. Here we review …
Polyunsaturated fatty acids and membrane organization: elucidating mechanisms to balance immunotherapy and susceptibility to infection
SR Shaikh, M Edidin - Chemistry and Physics of Lipids, 2008 - Elsevier
Polyunsaturated fatty acids (PUFAs), notably of the n-3 series, have immunosuppressive
effects which make these molecules candidates for treating inflammatory symptoms …
effects which make these molecules candidates for treating inflammatory symptoms …
Polyunsaturated fatty acids block dendritic cell activation and function independently of NF-κB activation
M Zeyda, MD Säemann, KM Stuhlmeier… - Journal of Biological …, 2005 - ASBMB
Polyunsaturated fatty acids (PUFAs) modulate immune responses leading to clinically
significant beneficial effects in a variety of inflammatory disorders. PUFA effects on T cells …
significant beneficial effects in a variety of inflammatory disorders. PUFA effects on T cells …
n− 3 Fatty acids uniquely affect anti-microbial resistance and immune cell plasma membrane organization
It is now well established that dietary lipids are incorporated into macrophage and T-cell
membrane microdomains, altering their structure and function. Within cell membranes, there …
membrane microdomains, altering their structure and function. Within cell membranes, there …
Unsaturated fatty acids and their immunomodulatory properties
S Coniglio, M Shumskaya, E Vassiliou - Biology, 2023 - mdpi.com
Simple Summary Diet can influence human health in both positive and negative ways. Ω-3
polyunsaturated fatty acids have an overall positive effect on humans. The sources of these …
polyunsaturated fatty acids have an overall positive effect on humans. The sources of these …
Dietary docosahexaenoic acid suppresses T cell protein kinase Cθ lipid raft recruitment and IL-2 production
YY Fan, LH Ly, R Barhoumi, DN McMurray… - The Journal of …, 2004 - journals.aai.org
To date, the proximal molecular targets through which dietary n-3 polyunsaturated fatty acids
(PUFA) suppress the inflammatory process have not been elucidated. Because cholesterol …
(PUFA) suppress the inflammatory process have not been elucidated. Because cholesterol …
Omega-3 fatty acids, lipid rafts, and T cell signaling
Abstract n-3 polyunsaturated fatty acids (PUFA) have been shown in many clinical studies to
attenuate inflammatory responses. Although inflammatory responses are orchestrated by a …
attenuate inflammatory responses. Although inflammatory responses are orchestrated by a …