Formulation strategies for folate-targeted liposomes and their biomedical applications
P Kumar, P Huo, B Liu - Pharmaceutics, 2019 - mdpi.com
The folate receptor (FR) is a tumor-associated antigen that can bind with folic acid (FA) and
its conjugates with high affinity and ingests the bound molecules inside the cell via the …
its conjugates with high affinity and ingests the bound molecules inside the cell via the …
Folate receptor-targeted liposomes as vectors for therapeutic agents
MA Gosselin, RJ Lee - 2002 - Elsevier
The folate receptor is a cell surface protein that has recently been identified as a tumor
marker, due to its differential overexpression in several malignancies. Current research …
marker, due to its differential overexpression in several malignancies. Current research …
Targeted delivery of nucleic acids into xenograft tumors mediated by novel folate-equipped liposomes
TO Kabilova, EV Shmendel, DV Gladkikh… - European Journal of …, 2018 - Elsevier
Folate receptors (FR) are cellular markers highly expressed in various cancer cells. Here,
we report on the synthesis of a novel folate-containing lipoconjugate (FC) built of 1, 2-di-O …
we report on the synthesis of a novel folate-containing lipoconjugate (FC) built of 1, 2-di-O …
Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid–PEG conjugates
A Gabizon, H Shmeeda, AT Horowitz… - Advanced drug delivery …, 2004 - Elsevier
Targeting of liposomes with phospholipid-anchored folate conjugates is an attractive
approach to deliver chemotherapeutic agents to folate receptor (FR) expressing tumors. The …
approach to deliver chemotherapeutic agents to folate receptor (FR) expressing tumors. The …
Synthesis and evaluation of a novel ligand for folate-mediated targeting liposomes
Folate receptors (FRs) have been identified as cellular surface markers for cancer and
leukemia. Liposomes containing lipophilic derivatives of folate have been shown to …
leukemia. Liposomes containing lipophilic derivatives of folate have been shown to …
Design and development of folate appended liposomes for enhanced delivery of 5-FU to tumor cells
Y Gupta, A Jain, P Jain, SK Jain - Journal of drug targeting, 2007 - Taylor & Francis
Folate appended sterically-stabilized liposomes (FA–SL) were investigated for tumor
targeting. Liposomes were prepared using HSPC, cholesterol and FA–polyethylene glycol …
targeting. Liposomes were prepared using HSPC, cholesterol and FA–polyethylene glycol …
Tumour-selective drug delivery via folate receptor-targeted liposomes
X Pan, RJ Lee - Expert opinion on drug delivery, 2004 - Taylor & Francis
Tumour cell-targeted liposomal delivery has the potential to enhance the therapeutic efficacy
and reduce the toxicity of anticancer agents. Folate receptor (FR) expression is frequently …
and reduce the toxicity of anticancer agents. Folate receptor (FR) expression is frequently …
Folate-targeted liposomes for drug delivery
The folate receptor has been identified as a marker for ovarian carcinomas and is also up-
regulated in many other types of cancer. Folate-conjugation has been successfully applied …
regulated in many other types of cancer. Folate-conjugation has been successfully applied …
Preparation, therapeutic efficacy and intratumoral localization of targeted daunorubicin liposomes conjugating folate-PEG-CHEMS
Folate polyethylene glycol-cholesterol hemisuccinate (folate-PEG-CHEMS) is a novel folate
ligand firstly synthesized by our group and demonstrated good stability and potential …
ligand firstly synthesized by our group and demonstrated good stability and potential …
Functional coating of liposomes using a folate–polymer conjugate to target folate receptors
K Watanabe, M Kaneko, Y Maitani - International journal of …, 2012 - Taylor & Francis
Folate-polymer-coated liposomes were developed for targeted chemotherapy using
doxorubicin (DXR) as a model drug. Folate-poly (L-lysine)(F–PLL) conjugates with a folate …
doxorubicin (DXR) as a model drug. Folate-poly (L-lysine)(F–PLL) conjugates with a folate …