Introduction: Dyslipidemia is an abnormal condition of blood lipid levels with a global
prevalence of 31.2% which can cause various complications including atherosclerosis that …

Rationale: Elevated plasma triglyceride levels have been recognized as a risk factor for the
development of coronary heart disease. Apolipoprotein C-III (apoC-III) represents both an …

Background ApoC-III plays a pivotal role in regulating plasma triglyceride (TG) levels by
inhibiting the hydrolysis of TG-rich lipoproteins and the receptor-mediated uptake of …

Elevated triglyceride levels (higher than~ 1000 mg/dL) are associated with an increased risk
for pancreatitis. Apolipoprotein-CIII (apoC-III) plays a key role in the metabolism of …

Abstract Aims Elevated apolipoprotein C-III (apoC-III) levels are associated with
hypertriglyceridaemia and coronary heart disease. AKCEA-APOCIII-LRx is an N-acetyl …

Apolipoprotein C-III has been referred to as an important participant in the metabolism of
triglyceride-rich lipoproteins, leading to hypertriglyceridemia and thereafter cardiovascular …

Hypertriglyceridemia is a common feature of many metabolic disorders and has been
identified as risk factor for cardiovascular disease. ApoC-III is commonly associated with …

In this review, firstly we will summarize the molecular function of ApoCIII in lipoprotein
metabolism. Then, we will examine the lipid-lowering potential of the pharmacological …

Background Apolipoprotein C-III (APOC3) is a key regulator of plasma triglyceride levels.
Elevated triglyceride levels are associated with a risk of adverse cardiovascular events and …

Background ApoC-III is synthesized principally by the liver, plays a pivotal role in regulating
plasma triglyceride (TG) levels and is causally associated with CVD. ApoC-III inhibits the …