Nanomedicine I: In vitro and in vivo evaluation of paclitaxel loaded poly-(ε-caprolactone), poly (dl-lactide-co-glycolide) and poly (dl-lactic acid) matrix nanoparticles in …

S VasanthaKumar, HN Ahamed, RN Saha - European Journal of Drug …, 2015 - Springer
Progress in nanoscience and nanotechnology laid foundation for nanotherapy-based
approach in cancer drug delivery for improved therapy and quality of life. The prepared …

Nanoparticles of biodegradable polymers for clinical administration of paclitaxel

SS Feng, L Mu, KY Win, G Huang - Current Medicinal Chemistry, 2004 - ingentaconnect.com
Paclitaxel is one of the best antineoplastic drugs found from nature in the past decades,
which has been found effective against a wide spectrum of cancers including ovarian …

Nanomedicine: nanoparticles of biodegradable polymers for cancer diagnosis and treatment

SS Feng - Cosmos, 2008 - World Scientific
Nanomedicine is to apply and further develop nanotechnology to solve problems in
medicine, ie to diagnose, treat and prevent diseases at the cellular and molecular level. This …

Fabrication and Character Study of the Anticancer Drug Paclitaxel (Taxol): PLGA nanoparticles-The benefaction for the modern therapeutic area

H Umamahesvari - Research Journal of Pharmacy and …, 2020 - indianjournals.com
Paclitaxel (Taxol) is one of the best antineoplastic drugs found from nature in the past
decades. Like many other anticancer drugs, there are difficulties in its clinical governance …

Enhanced oral bioavailability of paclitaxel formulated in vitamin E-TPGS emulsified nanoparticles of biodegradable polymers: in vitro and in vivo studies

L Zhao, SS Feng - Journal of pharmaceutical sciences, 2010 - Elsevier
This work evaluates the effects of paclitaxel loaded polymeric nanoparticles (NPs)
composed of poly (D, L-lactic-co-glycolic acid)(PLGA) with vitamin E TPGS as emulsifier for …

Development and characterization of paclitaxel-loaded PLGA nanoparticles and cytotoxicity assessment by MTT assay on A549 cell line

S Ünal, Ç Yücel, MÇ Tekeli, GŞ Karatoprak, Y Aktaş… - Proceedings, 2017 - mdpi.com
Paclitaxel (PTX) is a cytotoxic agent derived from Taxus brevifolia used for lung cancer. Poly
d, l-lactide-co-glycolide (PLGA) is an FDA-approved biodegradable polymer used for …

[PDF][PDF] Synergistic effect of Paclitaxel and Curcumin in nano-formulations on U87 and A549 cancer cell lines

J Praveena, SS Hakkimane… - J. Appl. Pharm. Sci, 2022 - pdfs.semanticscholar.org
Prolonged use of anticancer drug like Paclitaxel increases the level of transcription factor
nuclear factor kappa B (NFƘB) which increases drug resistance in cancer cells. Multi-drug …

Characterization, pharmacokinetics and disposition of novel nanoscale preparations of paclitaxel

C Wang, YJ Wang, YJ Wang, M Fan, F Luo… - International journal of …, 2011 - Elsevier
Polymeric nanoparticles (NPs) have great potential application in achieving targeted
delivery of anticancer drugs. Paclitaxel (PTX) loaded NPs were developed using …

The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly (lactide)–tocopheryl polyethylene glycol succinate …

Z Zhang, SS Feng - Biomaterials, 2006 - Elsevier
Paclitaxel is one of the most effective antineoplastic drugs. Its current clinical administration
is formulated in Cremophor EL, which causes serious side effects. Nanoparticle (NP) …

Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity

C Fonseca, S Simoes, R Gaspar - Journal of controlled release, 2002 - Elsevier
The main objective of this study was to develop a polymeric drug delivery system for
paclitaxel, intended to be intravenously administered, capable of improving the therapeutic …