Advances in materials-based therapeutic strategies against osteoporosis

C Lei, J Song, S Li, Y Zhu, M Liu, M Wan, Z Mu, FR Tay… - Biomaterials, 2023 - Elsevier
Osteoporosis is caused by the disruption in homeostasis between bone formation and bone
resorption. Conventional management of osteoporosis involves systematic drug …

Advances in Nanotechnology for the Treatment of Osteoporosis

M Barry, H Pearce, L Cross, M Tatullo… - Current osteoporosis …, 2016 - Springer
Osteoporosis is a degenerative bone disease commonly related to aging. With an increase
in life expectancies worldwide, the prevalence of the disease is expected to rise. Current …

Functional biomaterials for bone regeneration: a lesson in complex biology

AR Armiento, LP Hatt… - Advanced Functional …, 2020 - Wiley Online Library
Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Nano-based biomaterials as drug delivery systems against osteoporosis: a systematic review of preclinical and clinical evidence

F Salamanna, A Gambardella, D Contartese, A Visani… - Nanomaterials, 2021 - mdpi.com
Osteoporosis (OP) is one of the most significant causes of morbidity, particularly in post-
menopausal women and older men. Despite its remarkable occurrence, the search for an …

Bone as a structural material

EA Zimmermann, RO Ritchie - Advanced healthcare materials, 2015 - Wiley Online Library
As one of the most important natural materials, cortical bone is a composite material
comprising assemblies of tropocollagen molecules and nanoscale hydroxyapatite mineral …

On the road to smart biomaterials for bone research: Definitions, concepts, advances, and outlook

C Montoya, Y Du, AL Gianforcaro, S Orrego, M Yang… - Bone Research, 2021 - nature.com
The demand for biomaterials that promote the repair, replacement, or restoration of hard and
soft tissues continues to grow as the population ages. Traditionally, smart biomaterials have …

Bone targeting for the treatment of osteoporosis

T Luhmann, O Germershaus, J Groll… - Journal of controlled …, 2012 - Elsevier
Osteoporosis represents a major public health burden especially considering the aging
populations worldwide. Drug targeting will be important to better meet these challenges and …

Biomaterial scaffolds for treating osteoporotic bone

JA Sterling, SA Guelcher - Current osteoporosis reports, 2014 - Springer
Healing fractures resulting from osteoporosis or cancer remains a significant clinical
challenge. In these populations, healing is often impaired not only due to age and disease …

Advances in the application of mesenchymal stem cells, exosomes, biomimetic materials, and 3D printing in osteoporosis treatment

XY He, HM Yu, S Lin, YZ Li - Cellular & Molecular Biology Letters, 2021 - Springer
Owing to an increase in the aging population, osteoporosis has become a severe public
health concern, with a high prevalence among the elderly and postmenopausal adults …

The relevance of biomaterials to the prevention and treatment of osteoporosis

D Arcos, AR Boccaccini, M Bohner, A Díez-Pérez… - Acta biomaterialia, 2014 - Elsevier
Osteoporosis is a worldwide disease with a very high prevalence in humans older than 50.
The main clinical consequences are bone fractures, which often lead to patient disability or …