Interferometric scattering (iSCAT) microscopy and related techniques

RW Taylor, V Sandoghdar - Label-free super-resolution microscopy, 2019 - Springer
Interferometric scattering (iSCAT) microscopy is a powerful tool for label-free sensitive
detection and imaging of nanoparticles to high spatiotemporal resolution. As it was born out …

Interferometric scattering microscopy: seeing single nanoparticles and molecules via Rayleigh scattering

RW Taylor, V Sandoghdar - Nano letters, 2019 - ACS Publications
Fluorescence microscopy has been the workhorse for investigating optical phenomena at
the nanometer scale but this approach confronts several fundamental limits. As a result …

Interferometric scattering microscopy and its combination with single-molecule fluorescence imaging

J Ortega Arroyo, D Cole, P Kukura - Nature protocols, 2016 - nature.com
Interferometric scattering microscopy (iSCAT) is a light scattering-based imaging modality
that offers a unique combination of imaging speed and precision for tracking nanoscopic …

Label-free, ultrasensitive, ultrahigh-speed scattering-based interferometric imaging

CL Hsieh - Optics Communications, 2018 - Elsevier
Label-free microscope imaging techniques allow direct visualization of biological
substances in their most native forms. This review article provides an overview of recent …

Interferometric scattering microscopy

G Young, P Kukura - Annual review of physical chemistry, 2019 - annualreviews.org
Interferometric scattering microscopy (iSCAT) is an extremely sensitive imaging method
based on the efficient detection of light scattered by nanoscopic objects. The ability to, at …

Interferometric scattering microscopy (iSCAT): new frontiers in ultrafast and ultrasensitive optical microscopy

J Ortega-Arroyo, P Kukura - Physical Chemistry Chemical Physics, 2012 - pubs.rsc.org
Optical microscopes have for centuries been our window to the microscopic world. The
advent of single-molecule optics over the past few decades has ushered in a new era in …

Multiscale modeling and analysis for high-fidelity interferometric scattering microscopy

Y He, S Lin, HML Robert, H Li, P Zhang… - Journal of Physics D …, 2021 - iopscience.iop.org
Interferometric scattering microscopy (iSCAT), as an ultrasensitive fluorescence-free
imaging modality, has recently gained enormous attention and has been rapidly developing …

Bond-selective interferometric scattering microscopy

C Yurdakul, H Zong, Y Bai, JX Cheng… - Journal of Physics D …, 2021 - iopscience.iop.org
Interferometric scattering (iSCAT) microscopy has been a very promising technology for
highly sensitive label-free imaging of a broad spectrum of biological nanoparticles from …

Spinning disk interferometric scattering confocal microscopy captures millisecond timescale dynamics of living cells

YT Hsiao, TY Wu, BK Wu, SW Chu, CL Hsieh - Optics Express, 2022 - opg.optica.org
Interferometric scattering (iSCAT) microscopy is a highly sensitive imaging technique that
uses common-path interferometry to detect the linear scattering fields associated with …

Visualization of lipids and proteins at high spatial and temporal resolution via interferometric scattering (iSCAT) microscopy

S Spindler, J Ehrig, K König, T Nowak… - Journal of Physics D …, 2016 - iopscience.iop.org
Microscopy based on the interferometric detection of light scattered from nanoparticles
(iSCAT) was introduced in our laboratory more than a decade ago. In this work, we present …