Immunologic tolerance is the process whereby limits are placed on the degree to which
lymphocytes respond to an animal's inherent antigens. It is a quantitative rather than an …

" Imnlunological tolerance" may be described as a state of indifference or nonreactivity
towards a substance that would normally be expected to excite an immunological response …

The major histocompatibility complex (MHC) is a group of closely linked loci present in
remarkably similar form inall mammals and perhaps in all vertebrates. It plays a still …

Mice born and raised by mothers made specifically unresponsive to heterologous
erythrocytes by prior treatment with soluble extracts of these cells become themselves …

The maintenance of transplantation tolerance induced in adult mice after short-term
treatment with nonlytic monoclonal antibodies to CD4 and CD8 was investigated. CD4+ T …

This review seeks to explain the most exciting recent data concerning the nature of self/non‐
self discrimination by the immune system in a manner accessible to a biochemical …

Abstract Ehrlich (1906), with his usual perceptiveness, drew attention to the remarkable fact
that although vertebrates can readily be immunized with cells or body fluids from other …

The full potential of organ transplantation has not yet been realized because of the hazards
associated with the long-term use of immunosuppressive drugs. Modern research into …

Immunologic tolerance, the phenomenon whereby antigen interacts with the lymphoid
system to impair its later capacity to respond to that antigen, remains one of the most …

Immunological tolerance is a central phenomenon in immunology. It is generally supposed
that tolerance towards autologous antigens is acquired during the perinatal period in order …