Deciphering the DNA methylome of polycystic ovary syndrome

Q Tan - Molecular Diagnosis & Therapy, 2020 - Springer
Polycystic ovary syndrome (PCOS) is a hormonal disorder common among women of
reproductive age. PCOS is characterized by ovarian dysfunction and metabolic …

The epigenomics of polycystic ovarian syndrome: from pathogenesis to clinical manifestations

S Li, D Zhu, H Duan, Q Tan - Gynecological Endocrinology, 2016 - Taylor & Francis
Polycystic ovarian syndrome (PCOS) is a complex condition of ovarian dysfunction and
metabolic abnormalities with widely varying clinical manifestations resulting from …

[HTML][HTML] Differential DNA methylation patterns of polycystic ovarian syndrome in whole blood of Chinese women

S Li, D Zhu, H Duan, A Ren, D Glintborg, M Andersen… - Oncotarget, 2017 - ncbi.nlm.nih.gov
As a universally common endocrinopathy in women of reproductive age, the polycystic
ovarian syndrome is characterized by composite clinical phenotypes reflecting the …

[HTML][HTML] Genome-wide DNA methylation and gene expression patterns provide insight into polycystic ovary syndrome development

XX Wang, JZ Wei, J Jiao, SY Jiang, DH Yu, D Li - Oncotarget, 2014 - ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
women. However, the epigenetic mechanism involved in PCOS progression remains largely …

Epigenetic association analysis of clinical sub-phenotypes in patients with polycystic ovary syndrome (PCOS)

VM Jacobsen, S Li, A Wang, D Zhu, M Liu… - Gynecological …, 2019 - Taylor & Francis
Polycystic ovarian syndrome (PCOS) is a complex disorder affecting up to 15–20% of
reproductive women. PCOS has recently been investigated using genome-wide association …

[PDF][PDF] Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process

NEH Mimouni, I Paiva, AL Barbotin, FE Timzoura… - Cell metabolism, 2021 - cell.com
Polycystic ovary syndrome (PCOS) is the most common reproductive and metabolic disorder
affecting women of reproductive age. PCOS has a strong heritable component, but its …

[HTML][HTML] Genome-wide screen of ovary-specific DNA methylation in polycystic ovary syndrome

YY Yu, CX Sun, YK Liu, Y Li, L Wang, W Zhang - Fertility and sterility, 2015 - Elsevier
Objective To compare genome-wide DNA methylation profiles in ovary tissue from women
with polycystic ovary syndrome (PCOS) and healthy controls. Design Case-control study …

Integrated analysis of DNA methylation and transcriptome profiling of polycystic ovary syndrome

L Liu, D He, Y Wang, M Sheng - Molecular Medicine …, 2020 - spandidos-publications.com
The present study aimed to identify potentially important biomarkers associated with
polycystic ovary syndrome (PCOS) by integrating DNA methylation with transcriptome …

Role of genomic DNA methylation in PCOS pathogenesis: a systematic review and meta-analysis involving case-controlled clinical studies

K Rawat, A Sandhu, V Gautam… - Molecular Human …, 2022 - academic.oup.com
Polycystic ovary syndrome (PCOS) is often associated with aberrant DNA methylation.
Despite the advances in diagnostics and treatment of PCOS, the pathophysiological …

[HTML][HTML] Characterization of DNA methylation and screening of epigenetic markers in polycystic ovary syndrome

P Cao, W Yang, P Wang, X Li… - Frontiers in cell and …, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine and metabolic disorder in
women, which is characterized by androgen excess, ovulation dysfunction, and polycystic …