Epigenetic modifications in eukaryotic genomes occur primarily in the form of 5-
methylcytosine (5 mC). These modifications are heavily involved in transcriptional …

DNA methylation is an epigenetic modification of DNA in which methyl groups are added at
the 5-carbon position of cytosine. Aberrant DNA methylation, which has been associated …

Detection of epigenetic markers, including 5-methylcytosine, is crucial due to their role in
gene expression regulation and due to the mounting evidence of aberrant DNA methylation …

Methylation at the 5-carbon position of the cytosine nucleotide base in DNA has been shown
to be a reliable diagnostic biomarker for carcinogenesis. Early detection of methylation and …

Nanopore sequencing meets epigenetics | Nature Methods Skip to main content Thank you for
visiting nature.com. You are using a browser version with limited support for CSS. To obtain …

Precise and efficient mapping of epigenetic markers on DNA may become an important
clinical tool for prediction and identification of ailments. Methylated CpG sites are involved in …

DNA methylation is an epigenetic modification involving the addition of a methyl group to
DNA, which is heavily involved in gene expression and regulation, thereby critical to the …

We report the profiling of the 5-methyl cytosine distribution within single genomic-sized DNA
molecules at a gene-relevant resolution. This method linearizes and stretches DNA …

Cytosine methylation and hydroxymethylation are both important epigenetic modifications of
DNA in mammalian cells. Therefore, profiling DNA (hydroxy) methylation across the genome …

DNA methylation is catalyzed by a family of DNA methyltransferases that play crucial roles in
various biological processes. Therefore, an ultrasensitive methyltransferase assay is highly …