Background & Aims Central neuromodulators (antidepressants, antipsychotics, and other
central nervous system− targeted medications) are increasingly used for treatment of …

Abstract Purpose of Review The functional gastrointestinal disorders, or disorders of gut-
brain interaction as defined by the Rome IV criteria, are the most common diagnostic entities …

The pathophysiology of functional gastrointestinal disorders (FGIDs) is still unclear and
various complex mechanisms have been suggested to be involved. In many cases …

Functional gastrointestinal disorders (FGIDs) have been re-named as disorders of gut-brain
interactions. These conditions are not only common in clinical practice, but also in the …

Background The importance of bi‐directional brain‐gut interactions in gastrointestinal illness
is increasingly being recognized, most prominently in the area of functional gastrointestinal …

Functional gastrointestinal disorders (FGIDs) are common and distressing. They are so
named because a defined pathophysiology in terms of structural or biochemical pathways is …

Functional gastrointestinal disorders (FGIDs), the most common diagnoses in
gastroenterology, are recognized by morphologic and physiological abnormalities that often …

Gut–brain dysregulation has been recognized by the scientific community as being crucial to
the understanding of chronic gastrointestinal conditions, and this has translated into the …

Recent advances in our understanding of basic neuroenteric mechanisms and the role of
effectors and transmitters in the brain-gut axis have provided opportunities to develop new …

Although functional gastrointestinal disorders (FGID) are common, their pathophysiology
remains incompletely understood. It is generally accepted that dysfunction of the …