Biosynthesis of fungal melanins and their importance for human pathogenic fungi

K Langfelder, M Streibel, B Jahn, G Haase… - Fungal genetics and …, 2003 - Elsevier
For more than 40 years fungi have been known to produce pigments known as melanins.
Predominantly these have been dihydroxyphenylalanine (DOPA)-melanin and …

Pathogenic properties of fungal melanins

MJ Butler, AW Day, JM Henson, NP Money - Mycologia, 2001 - Taylor & Francis
Melanins are complex black polymers of resonance stabilized cyclic subunits (including
indoles, phenols, hydroxynaphthalenes) and are notoriously intractable to chemical …

[PDF][PDF] Melanin pigments of fungi

TA Belozerskaya, NN Gessler… - Fungal …, 2017 - ndl.ethernet.edu.et
Fungi possess all kinds of melanins found in nature. These pigments are products of
polymerization of phenolic compounds. Phenolic precursors determine the polymerization …

Melanins in fungi: Types, localization and putative biological roles

AV Toledo, MEE Franco, SMY Lopez… - … and molecular plant …, 2017 - Elsevier
Melanin is a secondary metabolite made up by complex heterogeneous polymers. Several
classes of fungal melanins have been described like γ-glutaminyl-3, 4-dihydroxy-benzene …

Pathogenic roles for fungal melanins

ES Jacobson - Clinical microbiology reviews, 2000 - Am Soc Microbiol
Melanins represent virulence factors for several pathogenic fungi; the number of examples is
growing. Thus, albino mutants of several genera (in one case, mutated precisely in the …

Melanins and their importance in pathogenic fungi

MH Wheeler, AA Bell - Current topics in medical mycology, 1988 - Springer
Melanins are generally described as dark brown or black pigments of high molecular weight
formed by oxidative polymerization of phenolic compounds. Certain yellow, red, green …

[PDF][PDF] Genetic analysis of melanin-deficient, nonpathogenic mutants of Magnaporthe grisea

FG Chumley, B Valent - Mol. Plant-Microbe Interact, 1990 - apsnet.org
The fungus Magnaporthe grisea causes rice blast disease and gray leaf spot disease of
other grasses. Numerous M. grisea mutants that fail to produce the dark gray pigment typical …

Melanin as a virulence factor in pathogenic fungi.

A Polak - Mycoses, 1990 - europepmc.org
The pigment melanin is found universally in nature and is attributed to a variety of functions.
In some fungi it is thought to play a decisive role in the determination of virulence. This …

The contribution of melanin to microbial pathogenesis

JD Nosanchuk, A Casadevall - Cellular microbiology, 2003 - Wiley Online Library
Melanins are enigmatic pigments that are produced by a wide variety of microorganisms
including several species of pathogenic bacteria, fungi and helminthes. The study of …

The role of melanins in melanotic fungi for pathogenesis and environmental survival

HC Eisenman, EM Greer, CW McGrail - Applied microbiology and …, 2020 - Springer
Melanins provide fungi protection from environmental stressors, support their ecological
roles, and can confer virulence in pathogens. While the function, structure, and synthesis of …