Id family of helix-loop-helix proteins in cancer
J Perk, A Iavarone, R Benezra - Nature Reviews Cancer, 2005 - nature.com
Over the past few decades, biologists have identified key molecular signatures associated
with a wide range of human cancers. Recently, animal models have been particularly useful …
with a wide range of human cancers. Recently, animal models have been particularly useful …
The ID proteins: master regulators of cancer stem cells and tumour aggressiveness
A Lasorella, R Benezra, A Iavarone - Nature Reviews Cancer, 2014 - nature.com
Inhibitor of DNA binding (ID) proteins are transcriptional regulators that control the timing of
cell fate determination and differentiation in stem and progenitor cells during normal …
cell fate determination and differentiation in stem and progenitor cells during normal …
Role of Id family proteins in growth control
Y Yokota, S Mori - Journal of cellular physiology, 2002 - Wiley Online Library
Id proteins (inhibitors of DNA binding/differentiation) are negative regulators of basic helix‐
loop‐helix (bHLH) type transcription factors, which promote the differentiation of various cell …
loop‐helix (bHLH) type transcription factors, which promote the differentiation of various cell …
Id-1 expression and cell survival
YC Wong, X Wang, MT Ling - Apoptosis, 2004 - Springer
The Id (inhibitor of differentiation or DNA binding) helix-loop-helix (HLH) proteins are a
group of dominant negative regulators of basic HLH transcriptional factors which promote …
group of dominant negative regulators of basic HLH transcriptional factors which promote …
Id proteins at the cross-road of development and cancer
A Lasorella, T Uo, A Iavarone - Oncogene, 2001 - nature.com
A large body of evidence has been accumulated that demonstrates dominant effects of Id
proteins on different aspects of cellular growth. Generally, constitutive expression of Id not …
proteins on different aspects of cellular growth. Generally, constitutive expression of Id not …
ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis
JD Norton - Journal of cell science, 2000 - journals.biologists.com
The ubiquitously expressed family of ID helix-loop-helix (HLH) proteins function as dominant
negative regulators of basic HLH (bHLH) transcriptional regulators that drive cell lineage …
negative regulators of basic HLH (bHLH) transcriptional regulators that drive cell lineage …
Id genes and proteins as promising targets in cancer therapy
S Fong, RJ Debs, PY Desprez - Trends in molecular medicine, 2004 - cell.com
Since the identification of Id proteins more than a decade ago, much work has demonstrated
their regulatory roles in development, cell fate and lineage determination, proliferation …
their regulatory roles in development, cell fate and lineage determination, proliferation …
The multiple roles of Id-1 in cancer progression
MT Ling, X Wang, X Zhang, YC Wong - Differentiation, 2006 - Elsevier
Id-1 (Inhibitor of differentiation/DNA binding) is a member of the helix–loop–helix protein
family expressed in actively proliferating cells. It regulates gene transcription by …
family expressed in actively proliferating cells. It regulates gene transcription by …
The Id-protein family in developmental and cancer-associated pathways
C Roschger, C Cabrele - Cell Communication and Signaling, 2017 - Springer
Inhibitors of DNA binding and cell differentiation (Id) proteins are members of the large
family of the helix-loop-helix (HLH) transcription factors, but they lack any DNA-binding motif …
family of the helix-loop-helix (HLH) transcription factors, but they lack any DNA-binding motif …
Reassessment of id1 protein expression in human mammary, prostate, and bladder cancers using a monospecific rabbit monoclonal anti-id1 antibody
J Perk, I Gil-Bazo, Y Chin, P de Candia, JJS Chen… - Cancer research, 2006 - AACR
Id proteins are a class of dominant-negative antagonists of helix-loop-helix transcription
factors and have been shown to control differentiation of a variety of cell types in diverse …
factors and have been shown to control differentiation of a variety of cell types in diverse …