[HTML][HTML] Structural/functional matches and divergences of phytoprostanes and phytofurans with bioactive human oxylipins

S Medina, Á Gil-Izquierdo, T Durand, F Ferreres… - Antioxidants, 2018 - mdpi.com
Structure-activity relationship (SAR) constitutes a crucial topic to discover new bioactive
molecules. This approach initiates with the comparison of a target candidate with a molecule …

The value of legume foods as a dietary source of phytoprostanes and phytofurans is dependent on species, variety, and growing conditions

MC García‐García, M del Río Celestino… - European Journal of …, 2019 - Wiley Online Library
Bioactive phytoprostanes and phytofurans are synthesized in higher plants by non‐
enzymatic oxidation of α‐linolenic acid (C18: 3 n‐3), triggered by high concentrations of …

Evaluation of Phoenix dactylifera Edible Parts and Byproducts as Sources of Phytoprostanes and Phytofurans

S Medina, Á Gil-Izquierdo, IM Abu-Reidah… - Journal of Agricultural …, 2020 - ACS Publications
Even though traditionally date-fruit has been featured by a marginal use, mainly restricted to
its dietary intake, in recent years, it has raised the range of applications for this agro-food …

Sorting out the phytoprostane and phytofuran profile in vegetable oils

R Domínguez-Perles, Á Abellán, D León… - Food Research …, 2018 - Elsevier
Abstract Phytoprostanes (PhytoPs) and phytofurans (PhytoFs) are prostaglandin-like
compounds, contributing to defense signaling and prevention of cellular damage. These …

[HTML][HTML] Therapeutic potential of plant oxylipins

T Savchenko, E Degtyaryov, Y Radzyukevich… - International Journal of …, 2022 - mdpi.com
For immobile plants, the main means of protection against adverse environmental factors is
the biosynthesis of various secondary (specialized) metabolites. The extreme diversity and …

Bioactive plant oxylipins-based lipidomics in eighty worldwide commercial dark chocolates: Effect of cocoa and fatty acid composition on their dietary burden

D León-Perez, R Domínguez-Perles… - Microchemical …, 2020 - Elsevier
Abstract Phytoprostanes (PhytoPs) and phytofurans (PhytoFs) are plant oxylipins
(isoprostane-prostaglandin-like compounds) formed by the free radical-catalyzed oxidation …

[HTML][HTML] Phytoprostanes and phytofurans modulate COX-2-linked inflammation markers in LPS-stimulated THP-1 monocytes by lipidomics workflow

M Campillo, S Medina, F Fanti… - Free Radical Biology …, 2021 - Elsevier
Inflammation is a fundamental pathophysiological process which occurs in the course of
several diseases. The present work describes the capacity of phytoprostanes (PhytoPs) and …

Identification and quantification of phytoprostanes and phytofurans of coffee and cocoa by-and co-products

M Ruesgas-Ramón, MC Figueroa-Espinoza… - Food & function, 2019 - pubs.rsc.org
Phytoprostanes (PhytoPs) and phytofurans (PhytoFs) are isoprostanoids that result from the
peroxidation of α-linolenic acid and are biomarkers of oxidative stress in plants and humans …

A cautionary note on the correct structure assignment of phytoprostanes and the emergence of a new prostane ring system

U Jahn, JM Galano, T Durand - Prostaglandins, leukotrienes and essential …, 2010 - Elsevier
Considerable confusion exists about the correct structural representation of phytoprostanes
(PhytoP). Improper use of the different nomenclature systems leads to incorrect structure …

Total Synthesis and in Vivo Quantitation of Phytofurans Derived from α‐Linolenic Acid

C Cuyamendous, KS Leung… - European Journal of …, 2017 - Wiley Online Library
Phytoprostanes (PhytoPs) are produced in plants and seeds by non‐enzymatic free‐radical
pathways from α‐linolenic acid (ALA). We recently highlighted the formation of a new class …