Functional optical imaging techniques, such as diffuse optical imaging and spectroscopy
and laser speckle imaging (LSI), were used in research and clinical settings to measure …

The complex cerebrovascular network is critical to controlling local cerebral blood flow
(CBF) and maintaining brain homeostasis. Alzheimer's disease (AD) and neurological injury …

These are exciting times for the field of optical imaging of brain function. Rapid
developments in theory and technology continue to considerably advance understanding of …

Imaging blood flow or oxygenation changes using optical techniques is useful for monitoring
cortical activity in healthy subjects as well as in diseased states such as stroke or epilepsy …

Noninvasive, three-dimensional, and longitudinal imaging of cerebral blood flow (CBF) in
small animal models and ultimately in humans has implications for fundamental research …

Significance: Quantitative measures of blood flow and metabolism are essential for
improved assessment of brain health and response to ischemic injury. Aim: We demonstrate …

Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

A new set of techniques allows for the study of brain function by near‐infrared light,
exploiting two optical phenomena: Changes in light absorption are determined by changes …

Monitoring brain function with light in vivo has become a reality. The technology of detecting
and interpreting patterns of reflected light has reached a degree of maturity that now permits …

Several functional brain mapping techniques have been developed over the past 3 decades
which have revolutionized our ability to map activity in the living brain, including positron …