[HTML][HTML] Therapeutic applications of curcumin for patients with pancreatic cancer

M Kanai - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
A number of preclinical studies have demonstrated anticancer effects for curcumin in various
types of tumors, including pancreatic cancer. Curcumin has anticancer effects both alone …

Curcumin anticancer studies in pancreatic cancer

S Bimonte, A Barbieri, M Leongito, M Piccirillo… - Nutrients, 2016 - mdpi.com
Pancreatic cancer (PC) is one of the deadliest cancers worldwide. Surgical resection
remains the only curative therapeutic treatment for this disease, although only the minority of …

Phase II trial of curcumin in patients with advanced pancreatic cancer

N Dhillon, BB Aggarwal, RA Newman, RA Wolff… - Clinical cancer …, 2008 - AACR
Purpose: Pancreatic cancer is almost always lethal, and the only US Food and Drug
Administration–approved therapies for it, gemcitabine and erlotinib, produce objective …

Phase II clinical trial of curcumin in patients with advanced pancreatic cancer

N Dhillon, RA Wolff, JL Abbruzzese… - Journal of Clinical …, 2006 - ascopubs.org
14151 Background: Pancreatic cancer is virtually always lethal, and the only FDA-approved
therapies-gemcitabine and erlotinib-produce objective responses in less than 10% of …

Curcumin and gemcitabine in patients with advanced pancreatic cancer

R Epelbaum, M Schaffer, B Vizel, V Badmaev… - Nutrition and …, 2010 - Taylor & Francis
Curcumin has a potent antiproliferative activity and can also potentiate the antitumor effect of
gemcitabine. This study was undertaken to evaluate the activity and feasibility of …

Curcumin analogs: Their roles in pancreatic cancer growth and metastasis

GP Nagaraju, L Benton, SR Bethi… - … Journal of Cancer, 2019 - Wiley Online Library
Curcumin is a polyphenolic constituent of turmeric that is known to have various molecular
effects in preclinical models, leading to prevention and anticancer properties. In clinical …

Therapeutic potential of curcumin in treatment of pancreatic cancer: current status and future perspectives

M Hosseini, SM Hassanian… - Journal of cellular …, 2017 - Wiley Online Library
Pancreatic cancer is among the leading cause of deaths due to cancer with extremely poor
prognosis. Gemcitabine is being used in the treatment of patient with pancreatic ductal …

[PDF][PDF] The dark side of curcumin

E Burgos‐Morón, JM Calderón‐Montaño… - International journal of …, 2010 - Citeseer
Dear Editor, Curcumin is a yellow–orange pigment obtained from the plant Curcuma longa.
The powdered rhizome of this plant, called turmeric, is a common ingredient in curry …

A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients

M Kanai, Y Otsuka, K Otsuka, M Sato… - Cancer chemotherapy …, 2013 - Springer
Background A growing number of preclinical studies have demonstrated that curcumin could
be a promising anticancer drug; however, poor bioavailability has been the major obstacle …

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer

M Kanai, K Yoshimura, M Asada, A Imaizumi… - Cancer chemotherapy …, 2011 - Springer
Purpose Curcumin, a plant-derived natural polyphenol, could be a promising anti-cancer
drug and shows synergic effects with cytotoxic agents. We evaluated the safety and …