Signaling factors potentially associated to the pathogenesis of adult T-cell leukemia/lymphoma: a network-analysis and novel findings assessment

SH Mozhgani, MZ Ghobadi, M Norouzi, H Rahimi… - Virus research, 2022 - Elsevier
Adult T-cell leukemia/lymphoma (ATLL) is a human T-cell leukemia virus (HTLV) type 1-
associated disease of TCD4+ cell transformation. Despite extensive studies on ATLL …

[HTML][HTML] Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach

MM Forghani-Ramandi, B Mostafavi, A Bahavar… - Virus Research, 2023 - Elsevier
Background Adult T-cell leukemia/lymphoma (ATLL) is a poor prognosis malignancy of
peripheral T-cells caused by human T-cell leukemia virus type 1 (HTLV-1). The low survival …

Deciphering microRNA-mRNA regulatory network in adult T-cell leukemia/lymphoma; the battle between oncogenes and anti-oncogenes

MZ Ghobadi, R Emamzadeh, SH Mozhgani - Plos one, 2021 - journals.plos.org
Adult T-cell leukemia/lymphoma (ATLL) is virus-caused cancer that originates from the
infection by human T-cell leukemia virus type 1. ATLL dysregulates various biological …

Potential miRNA-gene interactions determining progression of various ATLL cancer subtypes after infection by HTLV-1 oncovirus

MZ Ghobadi, E Afsaneh, R Emamzadeh… - BMC Medical …, 2023 - Springer
Abstract Background Adult T-cell Leukemia/Lymphoma (ATLL) is a rapidly progressing type
of T-cell non-Hodgkin lymphoma that is developed after the infection by human T-cell …

Molecular insight into the study of adult T-cell leukemia/lymphoma (ATLL): Ten-year studies on HTLV-1 associated diseases in an endemic region

F Ashrafi, M Rahimzada, M Parandi, A Mirhosseini… - Gene, 2022 - Elsevier
The outcome of successful infection, including human T-cell leukemia virus type 1 (HTLV-1),
is determined by the interactions between the host and the infectious agent. Ten years of …

Clinical applications of genomic alterations in ATLL: predictive markers and therapeutic targets

N Yoshida, H Miyoshi, K Ohshima - Cancers, 2021 - mdpi.com
Simple Summary In this review paper, we aim to summarize recent findings of genomic
alterations found in adult T-cell leukemia/lymphoma (ATLL), which is an incurable disease …

[HTML][HTML] Evaluation of the role of TAX, HBZ, and HTLV-1 proviral load on the survival of ATLL patients

MM Akbarin, A Shirdel, A Bari, ST Mohaddes… - Blood …, 2017 - ncbi.nlm.nih.gov
Background Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very
poor prognosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV …

Comprehensive high-throughput meta-analysis of differentially expressed microRNAs in transcriptomic datasets reveals significant disruption of MAPK/JNK signal …

S Shadabi, N Delrish, M Norouzi, M Ehteshami… - Infectious Agents and …, 2021 - Springer
Background Human T-lymphotropic virus 1 (HTLV-1) infection may lead to the development
of Adult T-cell leukemia/lymphoma (ATLL). To further elucidate the pathophysiology of this …

Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)

S Ahmadi Ghezeldasht, DJ Blackbourn… - Critical Reviews in …, 2023 - Taylor & Francis
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T
lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was …

HTLV-1-host interactions on the development of adult T cell leukemia/lymphoma: virus and host gene expressions

H Tarokhian, H Rahimi, A Mosavat, A Shirdel… - BMC cancer, 2018 - Springer
Background Adult T-cell leukemia/lymphoma (ATLL) is a lymphoproliferative disorder of
HTLV-1-host interactions in infected TCD4+ cells. In this study, the HTLV-1 proviral load …