New insights in the pathogenesis and treatment of normal tension glaucoma

M Mozaffarieh, J Flammer - Current opinion in pharmacology, 2013 - Elsevier
Increased intraocular pressure (IOP) is a major risk factor for glaucomatous damage and
reducing IOP improves prognosis. Nevertheless, there is little doubt that other risk factors …

Is there more to glaucoma treatment than lowering IOP?

M Mozaffarieh, J Flammer - Survey of ophthalmology, 2007 - Elsevier
Classic glaucoma treatment focuses on intraocular pressure (IOP) reduction. Better
knowledge of the pathogenesis of the disease has opened up new therapeutical …

Normal-tension glaucoma: is it different from primary open-angle glaucoma?

MB Shields - Current opinion in ophthalmology, 2008 - journals.lww.com
In clinical practice, control of IOP remains the mainstay of managing NTG patients, but
consideration must also be given to other factors, especially those that may influence …

New directions in the treatment of normal tension glaucoma

BJ Song, J Caprioli - Indian journal of ophthalmology, 2014 - journals.lww.com
Glaucoma is a progressive optic neuropathy that causes characteristic changes of the optic
nerve and visual field in relation to intraocular pressure (IOP). It is now known that glaucoma …

Pharmacotherapies for glaucoma

CB Toris - Current molecular medicine, 2010 - ingentaconnect.com
Glaucoma is a group of progressive optic neuropathies in which the axons in the optic nerve
are injured, retinal ganglion cell numbers are reduced and vision is gradually and …

Dysfunctional regulation of ocular blood flow: A risk factor for glaucoma?

D Moore, A Harris, D WuDunn, N Kheradiya… - Clinical …, 2008 - Taylor & Francis
Primary open angle glaucoma (OAG) is a multifactorial optic neuropathy characterized by
progressive retinal ganglion cell death and associated visual field loss. OAG is an emerging …

Target pressures in glaucoma

T Zeyen - Pathogenesis and Risk factors of Glaucoma, 1999 - Springer
Despite exciting progress in the field of neuroprotection, lowering the intraocular pressure
(IOP) is still the only available option to treat glaucoma patients. Several studies have shown …

The role of blood pressure in glaucoma

Z He, AJ Vingrys, JA Armitage… - Clinical and Experimental …, 2011 - Taylor & Francis
Although intraocular pressure (IOP) remains an important risk factor for glaucoma, it is clear
that other factors can also influence disease development and progression. More recently …

Intraocular pressure homeostasis: maintaining balance in a high-pressure environment

TS Acott, MJ Kelley, KE Keller, JA Vranka… - Journal of Ocular …, 2014 - liebertpub.com
Although glaucoma is a relatively common blinding disease, most people do not develop
glaucoma. A robust intraocular pressure (IOP) homeostatic mechanism keeps ocular …

New paradigms in the mechanisms and management of glaucoma

HA Quigley - Eye, 2005 - nature.com
During the last 30 years, the definition of glaucoma as been revised to eliminate the
inclusion of intraocular pressure. Open angle glaucoma is the second leading cause of …