Natural products: The role and mechanism in low‐density lipoprotein oxidation and atherosclerosis

S Zhang, L Li, W Chen, S Xu, X Feng… - Phytotherapy …, 2021 - Wiley Online Library
Atherosclerosis is a chronic inflammatory, metabolic, and epigenetic disease, which leads to
the life‐threatening coronary artery disease. Emerging studies from bench to bedside have …

The potential protective effects of phenolic compounds against low-density lipoprotein oxidation

R Amarowicz, RB Pegg - Current pharmaceutical design, 2017 - ingentaconnect.com
Background: The exact mechanism (s) of atherosclerosis in humans remains elusive, but
one theory hypothesizes that this deleterious process results from the oxidative modification …

Lycopene synergistically inhibits LDL oxidation in combination with vitamin E, glabridin, rosmarinic acid, carnosic acid, or garlic

B Fuhrman, N Volkova, M Rosenblat… - Antioxidants and Redox …, 2000 - liebertpub.com
Several lines of evidence suggest that oxidatively modified low-density lipoprotein (LDL) is
atherogenic, and that atherosclerosis can be attenuated by natural antioxidants, which …

Polyphenols and atherosclerosis: A critical review of clinical effects on LDL oxidation

A Ahmadi, T Jamialahmadi, A Sahebkar - Pharmacological Research, 2022 - Elsevier
Atherosclerosis is a major etiology of cardiovascular disease that causes considerable
mortality. Oxidized low-density lipoprotein (oxLDL) is a fundamental attributor to …

Flavonoids protect LDL from oxidation and attenuate atherosclerosis

B Fuhrman, M Aviram - Current opinion in lipidology, 2001 - journals.lww.com
Consumption of some plant-derived flavonoids results in their absorption and appearance in
plasma and tissues. The inverse relationship between dietary flavonoids consumption and …

Anti-oxidant effect of flavonoids on the susceptibility of LDL oxidation

GA Naderi, S Asgary, GN Sarraf-Zadegan… - Vascular …, 2003 - Springer
In vitro studies have demonstrated increased atherogenicity of oxidized low-density
lipoprotein (ox-LDL) compared to native LDL. Oxidative modification of LDL alters its …

Synergistic effects of phenolics and carotenoids on human low‐density lipoprotein oxidation

J Milde, EF Elstner, J Graßmann - Molecular nutrition & food …, 2007 - Wiley Online Library
Low‐density lipoprotein oxidation is believed to play an important role in the development of
atherosclerosis and therefore a high resistance of LDL against oxidation may prevent …

Polyphenolic flavonoids inhibit macrophage-mediated oxidation of LDL and attenuate atherogenesis

M Aviram, B Fuhrman - Atherosclerosis, 1998 - Elsevier
Macrophage-mediated oxidation of LDL, a hallmark in early atherosclerosis, depends on the
oxidative state of the LDL, and that of the macrophages. The LDL oxidative state is …

Additive or synergetic effects of phenolic compounds on human low density lipoprotein oxidation

TL Cirico, ST Omaye - Food and Chemical Toxicology, 2006 - Elsevier
The in vitro assessment of the antioxidant capacity of four phenolic compounds; catechin,
hesperidin, ferulic acid, and quercetin was evaluated by the examination of their ability to …

Low density lipoprotein oxidation, antioxidants, and atherosclerosis

AL Catapano, FM Maggi, E Tragni - Current opinion in cardiology, 2000 - journals.lww.com
Oxidized low density lipoproteins (LDLs) are believed to be the most atherogenic form of
LDL. However, although a number of experimental data support this concept, the protective …