Human papilloma virus DNAs immortalize normal human mammary epithelial cells and reduce their growth factor requirements.
V Band, D Zajchowski, V Kulesa… - Proceedings of the …, 1990 - National Acad Sciences
Human papilloma virus (HPV) types 16 and 18 are most commonly associated with cervical
carcinoma in patients and induce immortalization of human keratinocytes in culture. HPV …
carcinoma in patients and induce immortalization of human keratinocytes in culture. HPV …
Differential effects of human papillomavirus type 6, 16, and 18 DNAs on immortalization and transformation of human cervical epithelial cells.
G Pecoraro, D Morgan… - Proceedings of the …, 1989 - National Acad Sciences
The human papillomaviruses (HPVs) are associated with specific benign and malignant
lesions of the skin and mucosal epithelia. Cloned viral DNAs from HPV types 6b, 16, and 18 …
lesions of the skin and mucosal epithelia. Cloned viral DNAs from HPV types 6b, 16, and 18 …
Genetic Analysis of in Vitro Progression of Human Papillomavirus-transfected Human Cervical Cells
TM Chen, G Pecoraro, V Defendi - Cancer research, 1993 - AACR
The authors have established an in vitro model system which demonstrates the progression
of the transformed phenotypes of human cervical epithelial cells transfected with human …
of the transformed phenotypes of human cervical epithelial cells transfected with human …
Immortalization of primary human epithelial cells by cloned cervical carcinoma DNA containing human papillomavirus type 16 E6/E7 open reading frames
P Kaur, JK McDougall, R Cone - Journal of general …, 1989 - microbiologyresearch.org
Primary human epithelial cells were transfected with a subgenomic fragment of DNA cloned
from a cervical carcinoma, containing the putative transforming genes E6 and E7 from the …
from a cervical carcinoma, containing the putative transforming genes E6 and E7 from the …
Characterization of Normal Human Exocervical Epithelial Cells Immortalized in Vitro by Papillomavirus Types 16 and 18 DNA
CD Woodworth, PE Bowden, J Doniger, L Pirisi… - Cancer research, 1988 - AACR
An in vitro system for studying the interaction between human papillomavirus (HPV) 16 and
18 recombinant DNA and normal human exocervical epithelial cells is described. Eight HPV …
18 recombinant DNA and normal human exocervical epithelial cells is described. Eight HPV …
The E7 open reading frame of human papillomavirus type 16 encodes a transforming gene.
KH Vousden, J Doniger, JA DiPaolo… - Oncogene research, 1988 - europepmc.org
Prior analysis of bovine papillomavirus has identified two genes, E5 and E6, which induce
morphologic transformation of certain established cells. To study the transforming genes of …
morphologic transformation of certain established cells. To study the transforming genes of …
Continuous cell lines with altered growth and differentiation properties originate after transfection of human keratinocytes with human papillomavirus type 16 DNA
L Pirisi, KE Creek, J Doniger, JA Dipaolo - Carcinogenesis, 1988 - academic.oup.com
Immortalization of human keratinocytes (HKc) by human papillomavirus type 16 (HPV16) is
reproducible at a high frequency, is due directly to the presence of the viral sequences in the …
reproducible at a high frequency, is due directly to the presence of the viral sequences in the …
Suppression in vivo of human papillomavirus type 18 E6-E7 gene expression in nontumorigenic HeLa X fibroblast hybrid cells
FX Bosch, E Schwarz, P Boukamp, NE Fusenig… - Journal of …, 1990 - Am Soc Microbiol
The E6 and E7 genes of the cancer-associated human papillomavirus (HPV) types 16
(HPV16) and 18 (HPV18) can induce cell immortalization in vitro in normal human …
(HPV16) and 18 (HPV18) can induce cell immortalization in vitro in normal human …
Immortalization and transformation of human cells by human papillomavirus
JK McDougall - Human Pathogenic Papillomaviruses, 1994 - Springer
The association of human papillomaviruses (HPVs) with anogenital cancer is now supported
by such overwhelming evidence that even the most sceptical critic of a virus/cancer …
by such overwhelming evidence that even the most sceptical critic of a virus/cancer …
Absence of HPV 16 and 18 DNA in breast cancer
D Wrede, YA Luqmani, RC Coombes… - British journal of …, 1992 - nature.com
The finding that human papillomavirus (HPV) genes can immortalise breast epithelial cells
has led to suggestions that HPV could be involved in the pathogenesis of breast cancer …
has led to suggestions that HPV could be involved in the pathogenesis of breast cancer …