[HTML][HTML] Non-mulberry silk fibroin biomaterial for corneal regeneration

S Hazra, S Nandi, D Naskar, R Guha, S Chowdhury… - Scientific reports, 2016 - nature.com
Purpose: Successful repair of a damaged corneal surface is a great challenge and may
require the use of a scaffold that supports cell growth and differentiation. Amniotic …

[HTML][HTML] Silk fibroin in ocular surface reconstruction: what is its potential as a biomaterial in ophthalmics?

DG Harkin, TV Chirila - Future Medicinal Chemistry, 2012 - Future Science
Owing to sensitizing reactions which are attributed to the presence of sericin, currently the
latter is removed from the silk sutures. As such, BMSF can be easily isolated from sericin and …

[HTML][HTML] In vitro culture of human corneal endothelium on non-mulberry silk fibroin films for tissue regeneration

C Ramachandran, P Gupta, S Hazra… - … Vision Science & …, 2020 - iovs.arvojournals.org
Purpose: The purpose of this study was to determine if non-mulberry varieties of silk are
suitable for the culture of corneal endothelium (CE). Methods: Aqueous silk fibroin derived …

Silk fibroin film as an efficient carrier for corneal endothelial cells regeneration

EY Kim, N Tripathy, JY Park, SE Lee, CK Joo… - Macromolecular …, 2015 - Springer
Tissue engineered corneas are a promising alternative to the limited donor corneas for
transplantation. Here, we fabricated a transparent silk fibroin film with varied sericin content …

Silk as substratum for cell attachment and proliferation

TV Chirila, Z Barnard, Z Zainuddin… - Materials Science …, 2007 - Trans Tech Publ
Silk fibroin (SF), isolated from silkworm (Bombyx mori) cocoons, is a natural biodegradable
polymer. Over the past decade, there was some interest in using SF as a biomedical …

Fabrication of silk fibroin film using centrifugal casting technique for corneal tissue engineering

MC Lee, DK Kim, OJ Lee, JH Kim… - … Research Part B …, 2016 - Wiley Online Library
Films prepared from silk fibroin have shown potential as biomaterials in tissue engineering
applications for the eye. Here, we present a novel process for fabrication of silk fibroin films …

Oriented nanofibrous silk as a natural scaffold for ocular epithelial regeneration

E Biazar, A Baradaran-Rafii… - Journal of …, 2015 - Taylor & Francis
The aim of this study was to develop nanofibrous silk substrates for limbal stem cell
expansion that can serve as a potential alternative substrate to replace human amniotic …

[HTML][HTML] Treatment of silk fibroin with poly (ethylene glycol) for the enhancement of corneal epithelial cell growth

S Suzuki, RA Dawson, TV Chirila… - Journal of functional …, 2015 - mdpi.com
A silk protein, fibroin, was isolated from the cocoons of the domesticated silkworm (Bombyx
mori) and cast into membranes to serve as freestanding templates for tissue-engineered …

Bioengineered neo-corneal endothelium using collagen type-I coated silk fibroin film

EY Kim, N Tripathy, SA Cho, CK Joo, D Lee… - Colloids and Surfaces B …, 2015 - Elsevier
Corneal transplantation, a common surgical protocol for visual acuity improvement, is limited
owing to shortage of high quality donor corneas and/or lack of accurate replication of …

[HTML][HTML] Promising role of silk-based biomaterials for ocular-based drug delivery and tissue engineering

SUD Wani, MH Masoodi, SP Gautam, HG Shivakumar… - Polymers, 2022 - mdpi.com
Silk is a wonderful biopolymer that has a long history of medical applications. Surgical cords
and medically authorised human analogues made of silk have a long history of use in …