Diet-induced obesity alters skeletal microarchitecture and the endocrine activity of bone

NKY Wee, H Herzog… - Handbook of nutrition …, 2016 - wageningenacademic.com
Changes in whole body metabolism can have profound effects on bone mass. However, the
relationship between obesity and bone mass is complex. Weight gain increases mechanical …

[HTML][HTML] Obesity, osteoporosis and bone metabolism

K Gkastaris, DG Goulis, M Potoupnis… - … of musculoskeletal & …, 2020 - ncbi.nlm.nih.gov
Obesity and osteoporosis have become major global health problems over the last decades
as their prevalence is increasing. The interaction between obesity and bone metabolism is …

Obesity and bone metabolism

C Savvidis, S Tournis, AD Dede - Hormones, 2018 - Springer
The interaction between obesity and bone metabolism is complex. The effects of fat on the
skeleton are mediated by both mechanical and biochemical factors. Though obesity is …

Obesity is a concern for bone health with aging

SA Shapses, LC Pop, Y Wang - Nutrition research, 2017 - Elsevier
Accumulating evidence supports a complex relationship between adiposity and
osteoporosis in overweight/obese individuals, with local interactions and endocrine …

Effects of obesity on bone metabolism

JJ Cao - Journal of orthopaedic surgery and research, 2011 - Springer
Obesity is traditionally viewed to be beneficial to bone health because of well-established
positive effect of mechanical loading conferred by body weight on bone formation, despite …

Obesity and bone health: a complex link

J Hou, C He, W He, M Yang, X Luo, C Li - Frontiers in cell and …, 2020 - frontiersin.org
So far, the connections between obesity and skeleton have been extensively explored, but
the results are inconsistent. Obesity is thought to affect bone health through a variety of …

The obesity of bone

EA Greco, A Lenzi, S Migliaccio - Therapeutic advances in …, 2015 - journals.sagepub.com
During the last decades, obesity and osteoporosis have become important global health
problems, and the belief that obesity is protective against osteoporosis has recently come …

[HTML][HTML] Changes in bone mass associated with obesity and weight loss in humans: Applicability of animal models

VFH Jensen, AM Mølck, M Dalgaard, FE McGuigan… - Bone, 2021 - Elsevier
The implications of obesity and weight loss for human bone health are not well understood.
Although the bone changes associated with weight loss are similar in humans and rodents …

Augmenting functional adaptation: Does obesity have a systemic effect on bone strength properties in humans?

NM Reeves - 2014 - trace.tennessee.edu
This study considers the mechanical and neuroendocrine-metabolic effects of obesity on
cortical bone and joint morphology throughout the human skeleton. Obesity has primarily …

Cellular and molecular mechanisms associating obesity to bone loss

YS Forte, M Renovato-Martins, C Barja-Fidalgo - Cells, 2023 - mdpi.com
Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …