This systematic review evaluated the animal and human evidence for
pharmacomicrobiomics (PMx) interactions of antidepressant medications. Studies of gut …

Background Antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs)
and serotonin-norepinephrine reuptake inhibitors (SNRIs), are commonly prescribed for …

Background There is a growing body of evidence suggesting that disturbance of the gut-
brain axis may be one of the potential causes of major depressive disorder (MDD). However …

A major depressive disorder is a serious mental illness characterized by a pervasive low
mood that negatively concerns personal life, work life, or education, affecting millions of …

Background Antidepressants are a lifesaver for many people worldwide, regardless of their
age or gender. Antidepressant therapy has been the choice for patients with depression …

The microbiota-gut-brain axis has been shown to influence human health and diseases,
including depression. The interactions between drugs and intestinal microbiota are complex …

Objectives The first drug repurposed for the treatment of depression was the tuberculostatic
iproniazid. At present, drugs belonging to new classes of antidepressants still have …

Relationship between drugs and microbiota is bilateral. Proper composition thus function of
microbiota is a key to some medications used in modern medicine. However, there is also …

Antidepressant medications are known to modulate the central nervous system, and gut
microbiota can play a role in depression via microbiota–gut–brain axis. But the impact of …

The microbiome residing in the human gut performs a wide range of biological functions.
Recently, it has been elucidated that a change in dietary habits is associated with alteration …