Background: The morbidity and mortality of patients with functional mitral regurgitation (MR)
remain high, but no pharmacological therapy has been proven effective. The hypothesis of …

Objectives: The goal of this study was to determine the therapeutic efficacy of angiotensin-
converting enzyme (ACE) inhibitors and beta-adrenergic receptor blockers in experimental …

Aims To assess long‐term prognosis in patients with functional mitral regurgitation (FMR)
and left ventricular (LV) dysfunction, receiving current standard pharmacological therapy …

Two distinct pathways can lead to functional mitral regurgitation (MR) in patients with chronic
heart failure and a reduced ejection fraction. When remodeling and enlargement of the left …

OBJECTIVES This study was performed to define the rates and determinants of progression
of organic mitral regurgitation (MR). BACKGROUND Severe MR has major clinical …

Traditional approaches to the characterization of secondary or functional mitral regurgitation
(MR) have largely ignored the critical importance of the left ventricle (LV). We propose that …

Background The clinical outcome of asymptomatic mitral regurgitation is poorly defined, and
the treatment is uncertain. We studied the effect on the outcome of quantifying mitral …

BACKGROUND: Mitral regurgitation (MR) may develop in patients with advanced systolic
congestive heart failure (CHF) without organic mitral valve disease and contribute to …

BACKGROUND: This study aimed to assess the prognostic value of right ventricular (RV)
dysfunction in patients with secondary mitral regurgitation (MR) by simple methods of …

Functional mitral regurgitation (FMR) is associated with poor outcomes in patients with heart
failure (HF). However, it is not clear whether FMR is just a consequence of left ventricular …