[HTML][HTML] Spray congealing: An emerging technology to prepare solid dispersions with enhanced oral bioavailability of poorly water soluble drugs
S Bertoni, B Albertini, N Passerini - Molecules, 2019 - mdpi.com
The low and variable oral bioavailability of poorly water soluble drugs remains a major
concern for the pharmaceutical industry. Spray congealing is an emerging technology for the …
concern for the pharmaceutical industry. Spray congealing is an emerging technology for the …
Spray congealing: A versatile technology for advanced drug-delivery systems
S Bertoni, LS Dolci, B Albertini, N Passerini - Therapeutic delivery, 2018 - Taylor & Francis
Spray congealing is a low cost, simple and versatile method to produce microparticles
without the use of organic or aqueous solvent. This review provides a detailed picture of the …
without the use of organic or aqueous solvent. This review provides a detailed picture of the …
Application of spray-drying and electrospraying/electospinning for poorly watersoluble drugs: A particle engineering approach
Solid dispersions have been widely studied as an attractive formulation strategy for the
increasingly prevalent poorly watersoluble drug compounds, including herbal medicines …
increasingly prevalent poorly watersoluble drug compounds, including herbal medicines …
Spray drying as an advantageous strategy for enhancing pharmaceuticals bioavailability
AH Salama - Drug Delivery and Translational Research, 2020 - Springer
Spray drying is an efficient technique that is used not only for rapid evaporation of the
solvent from different systems but also for designing ultra-fine particles with various …
solvent from different systems but also for designing ultra-fine particles with various …
The influence of spray-drying parameters on phase behavior, drug distribution, and in vitro release of injectable microspheres for sustained release
J Meeus, M Lenaerts, DJ Scurr, K Amssoms… - Journal of …, 2015 - Elsevier
For ternary solid dispersions, it is indispensable to characterize their structure, phase
behavior, and the spatial distribution of the dispersed drug as this might influence the …
behavior, and the spatial distribution of the dispersed drug as this might influence the …
Manufacturing of solid dispersions of poorly water soluble drugs by spray drying: formulation and process considerations
Spray drying is an efficient technology for solid dispersion manufacturing since it allows
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …
extreme rapid solvent evaporation leading to fast transformation of an API-carrier solution to …
[HTML][HTML] Different BCS class II drug-gelucire solid dispersions prepared by spray congealing: Evaluation of solid state properties and in vitro performances
S Bertoni, B Albertini, N Passerini - Pharmaceutics, 2020 - mdpi.com
Delivery of poorly water soluble active pharmaceutical ingredients (APIs) by semi-crystalline
solid dispersions prepared by spray congealing in form of microparticles (MPs) is an …
solid dispersions prepared by spray congealing in form of microparticles (MPs) is an …
Enhanced solubility of poorly soluble drugs via spray drying
C Arpargaus, D Rütti, M Meuri - Drug Delivery Strategies for …, 2013 - Wiley Online Library
Spray drying is a simple, rapid, reproducible, and scalable drying technique, allowing mild
temperature conditions suited to heat‐sensitive biopharmaceutical compounds. Compared …
temperature conditions suited to heat‐sensitive biopharmaceutical compounds. Compared …
Better and greener: sustainable pharmaceutical manufacturing technologies for highly bioavailable solid dosage forms
S Bertoni, D Hasa, B Albertini, B Perissutti… - Drug Delivery and …, 2022 - Springer
In the last decades, Green Chemistry has been gaining widespread attention within the
pharmaceutical field. It is thus very important to bring more sustainable approaches into the …
pharmaceutical field. It is thus very important to bring more sustainable approaches into the …
Multicomponent solid dispersion a new generation of solid dispersion produced by spray-drying
LM De Mohac, B Raimi-Abraham, R Caruana… - Journal of Drug Delivery …, 2020 - Elsevier
The term “multicomponent solid dispersion” is widely used in recent literature to describe
solid formulations consisting of a special excipient's mixture and active molecules finely …
solid formulations consisting of a special excipient's mixture and active molecules finely …