Dietary phosphate, particularly inorganic phosphate, is an emerging risk factor for
hypertension which is ubiquitous in the western diet. Large randomized clinical trials are …

It has already been established that in end-stage renal disease, hyperphosphatemia causes
soft tissue calcification including vascular calcifications. It has also been supported that there …

The kidneys excrete excess dietary phosphate, and patients with chronic kidney disease
may suffer from phosphate overload and hyperphosphatemia. In chronic kidney disease …

It has recently been recognized that even in the normal population high normal phosphate
concentrations are associated with increased all-cause and cardiovascular mortality …

A complex system of endocrine and paracrine signals exists to control phosphate balance.
Dysregulation of these systems in patients with chronic kidney disease has serious clinical …

Hyperphosphatemia or even serum phosphate levels within the “normal laboratory range”
are highly associated with increased cardiovascular disease risk and mortality in the general …

High serum phosphate is linked to poor health outcome and mortality in chronic kidney
disease (CKD) patients before or after the initiation of dialysis. Therefore, maintenance of …

Chronic kidney disease (CKD) is prevalent affecting 8.5% of the population in the UK and it
is associated with premature cardiovascular disease (CVD) and death. The association …

Awareness of phosphorus intake is important because both phosphorus deficiency and
overloading impair bone health and quality of life. Phosphorus consumption is increasing in …

Hyperphosphatemia has consistently been shown to be associated with dismal outcome in a
wide variety of populations, particularly in chronic kidney disease (CKD). Compelling …