Platinum-based chemotherapy via nanocarriers and co-delivery of multiple drugs

C Xian, H Chen, F Xiong, Y Fang, H Huang… - Biomaterials Science, 2021 - pubs.rsc.org
Platinum-based anticancer drugs can inhibit the growth of cancer cells by disrupting DNA
replication, which makes them widely applicable in clinics for treating tumors and cancers …

Nanocarriers for delivery of platinum anticancer drugs

HS Oberoi, NV Nukolova, AV Kabanov… - Advanced drug delivery …, 2013 - Elsevier
Platinum based anticancer drugs have revolutionized cancer chemotherapy, and continue to
be in widespread clinical use especially for management of tumors of the ovary, testes, and …

[HTML][HTML] Advances in drug delivery system for platinum agents based combination therapy

X Kang, HH Xiao, HQ Song, XB Jing… - Cancer biology & …, 2015 - ncbi.nlm.nih.gov
Platinum-based anticancer agents are widely used as first-line drugs in cancer
chemotherapy for various solid tumors. However, great side effects and occurrence of …

Use of anticancer platinum compounds in combination therapies and challenges in drug delivery

X Xiao, JT Oswald, T Wang… - Current Medicinal …, 2020 - ingentaconnect.com
As one of the leading and most important metal-based drugs, platinum-based
pharmaceuticals are widely used in the treatment of solid malignancies. Despite significant …

[HTML][HTML] Nanocarriers for platinum drug delivery

Q Zhang, G Kuang, L Zhang, Y Zhu - Biomedical Technology, 2023 - Elsevier
Platinum drugs have been coined as one of the great success representatives in cancer
chemotherapy. With the accidental discovery of cisplatin, thousands of platinum-based …

Nanocarriers-mediated drug delivery systems for anticancer agents: an overview and perspectives

Z Edis, J Wang, MK Waqas, M Ijaz… - International journal of …, 2021 - Taylor & Francis
Nanotechnology has been actively integrated as drug carriers over the last few years to treat
various cancers. The main hurdle in the clinical management of cancer is the development …

Recent advances in nanocarriers for clinical platinum (II) anticancer drugs

JJ Zhang, QJ Xu, Y Zhang, Q Zhou, R Lv, Z Chen… - Coordination Chemistry …, 2024 - Elsevier
Platinum (II) drugs have been one of the most commonly used anticancer drugs in clinic.
However, drug resistance and severe toxic effects limit their clinical applications. Developing …

Lipid, polymeric, inorganic-based drug delivery applications for platinum-based anticancer drugs

T Boztepe, GR Castro, IE León - International journal of pharmaceutics, 2021 - Elsevier
The three main FDA-approved platinum drugs in chemotherapy such as carboplatin,
cisplatin, and oxaliplatin are extensively applied in cancer treatments. Although the clinical …

Nanocarriers: a reliable tool for the delivery of anticancer drugs

H Sabit, M Abdel-Hakeem, T Shoala, S Abdel-Ghany… - Pharmaceutics, 2022 - mdpi.com
Nanomedicines have gained popularity due to their potential therapeutic applications,
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …

Inorganic nano-targeted drugs delivery system and its application of platinum-based anticancer drugs

J Chen, C Gao, Y Zhang, T Wang… - … of Nanoscience and …, 2017 - ingentaconnect.com
As one of the most important anticancer drugs, cisplatin and its analogues have been widely
used in chemotherapy regimens of various tumors. However, a series of side effects and …