Crosstalk between lncRNAs in the apoptotic pathway and therapeutic targets in cancer

N Ebrahimi, S Parkhideh, S Samizade… - Cytokine & growth factor …, 2022 - Elsevier
The assertion that a significant portion of the mammalian genome has not been translated
and that non-coding RNA accounts for over half of polyadenylate RNA have received much …

LncRNAs: new players in apoptosis control

MN Rossi, F Antonangeli - International journal of cell biology, 2014 - Wiley Online Library
The discovery that the mammalian genome is largely transcribed and that almost half of the
polyadenylated RNAs is composed of noncoding RNAs has attracted the attention of the …

Progress in understanding the role of lncRNA in programmed cell death

N Jiang, X Zhang, X Gu, X Li, L Shang - Cell death discovery, 2021 - nature.com
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not
translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as …

LncRNAs in cancer: regulatory and therapeutic implications

A Nandwani, S Rathore, M Datta - Cancer letters, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) comprise a class of RNAs that do not code for proteins but
are critical in regulating diverse cellular processes and maintaining cell function. In doing so …

Molecular mechanisms of lncRNAs in the dependent regulation of cancer and their potential therapeutic use

C García-Padilla, Á Dueñas, V García-López… - International journal of …, 2022 - mdpi.com
Deep whole genome and transcriptome sequencing have highlighted the importance of an
emerging class of non-coding RNA longer than 200 nucleotides (ie, long non-coding RNAs …

Long noncoding RNAs in cancer and therapeutic potential

A Renganathan, E Felley-Bosco - Long Non Coding RNA Biology, 2017 - Springer
Long noncoding RNAs (lncRNAs) are the major elements of the mammalian transcriptome
that is emerging as a central player controlling diverse cellular mechanisms. Most of the well …

[HTML][HTML] LncRNAs: from basic research to medical application

T Wu, Y Du - International journal of biological sciences, 2017 - ncbi.nlm.nih.gov
This review aimed to summarize the current research contents about long noncoding RNAs
(lncRNAs) and some related lncRNAs as molecular biomarkers or therapy strategies in …

The application of lncRNAs in cancer treatment and diagnosis

Y Zhang, L Tang - Recent patents on anti-cancer drug …, 2018 - ingentaconnect.com
Background: It is increasingly evident that lncRNAs have various biological functions playing
as essential regulators, getting involved in diverse cellular processes. Many of the lncRNAs …

LncRNA as cancer biomarkers

I Iaccarino, W Klapper - Long Non-coding RNAs in Cancer, 2021 - Springer
Although the great majority of cancers share a defined group of hallmarks that is responsible
for the uncontrolled growth of particular cell types, it is today clear that under the name of …

LncRNAs in cancer: from garbage to junk

M Aprile, V Katopodi, E Leucci, V Costa - Cancers, 2020 - mdpi.com
Simple Summary Long non-coding RNAs (lncRNAs) are generally defined as transcripts
longer than 200 nucleotides and not coding for proteins. This review provides an overview of …