Background Transforming growth factor (TGF)-β signaling functions importantly in regulating
tumor microenvironment (TME). This study developed a prognostic gene signature based on …

Background Lung adenocarcinoma (LUAD) is the leading histological subtype of lung
cancer worldwide, causing high mortality each year. The tumor immune cell infiltration (ICI) …

Lung cancer is one of the most common malignant tumors, and ranks high in the list of
mortality due to cancers. Lung adenocarcinoma (LUAD) is the most common subtype of lung …

Background: Although immunotherapy with checkpoint inhibitors is changing the face of
lung adenocarcinoma (LUAD) treatments, only limited patients could benefit from it …

Background Immune therapy has become first-line treatment option for patients with lung
cancer, but some patients respond poorly to immune therapy, especially among patients …

The association between memory CD4+ T cells and cancer prognosis is increasingly
recognized, but their impact on lung adenocarcinoma (LUAD) prognosis remains unclear. In …

Epithelial-mesenchymal transition (EMT) process, which is regulated by genes of inducible
factors and transcription factor family of signaling pathways, transforms epithelial cells into …

Background: Lung adenocarcinoma (LUAD), the most common subtype of non-small cell
lung cancer (NSCLC), is associated with poor prognosis. However, current stage-based …

Lung adenocarcinoma (LUAD) is an essential pathological subtype of non-small cell lung
cancer and offers a severe problem for worldwide public health. There is mounting proof that …

There is a correlation between tumors and immunity with the degree of immune cell
infiltration in tumors being closely related to tumor growth and progression. Therefore, the …