Use of mixture design in drug-excipient compatibility determinations: Thymol nanoparticles case study
FQ Pires, T Angelo, JKR Silva, LCL Sá-Barreto… - … of pharmaceutical and …, 2017 - Elsevier
The objective of this work was to access thymol-excipient compatibility using an alternative
protocol of mixture design subsidizing the development of nanostructures lipid carriers …
protocol of mixture design subsidizing the development of nanostructures lipid carriers …
Drug-excipient compatibility testing using a high-throughput approach and statistical design
N Wyttenbach, C Birringer, J Alsenz… - Pharmaceutical …, 2005 - Taylor & Francis
The aim of our research was to develop a miniaturized high throughput drug-excipient
compatibility test. Experiments were planned and evaluated using statistical experimental …
compatibility test. Experiments were planned and evaluated using statistical experimental …
[PDF][PDF] Thermal Analysis as a Useful Tool in Drug-Excipient Compatibilty Studies: The Impact in Pharmaceuticals Products
D Dourado - Biomed. J. Sci. Tech. Res, 2019 - researchgate.net
This mini-review discusses the importance of thermal analysis as a predictive tool for
pharmaceutical stability in the design of drug-excipient compatibility studies. In this regard …
pharmaceutical stability in the design of drug-excipient compatibility studies. In this regard …
Drug–excipient compatibility screening—role of thermoanalytical and spectroscopic techniques
R Chadha, S Bhandari - Journal of pharmaceutical and biomedical …, 2014 - Elsevier
Estimation of drug–excipient interactions is a crucial step in preformulation studies of drug
development to achieve consistent stability, bioavailability and manufacturability of solid …
development to achieve consistent stability, bioavailability and manufacturability of solid …
Drug-excipient compatibility studies in formulation development: current trends and techniques
The safety, efficacy, quality and stability of a formulation are the cornerstones of any new
drug development process. In order to consistently maintain these attributes in a finished …
drug development process. In order to consistently maintain these attributes in a finished …
Drug–excipient interaction and incompatibilities
Pharmaceutical excipients are traditionally considered as pharmacologically inert
substances, but, can also actively participate in drug–excipient interactions, viz., physical …
substances, but, can also actively participate in drug–excipient interactions, viz., physical …
Ensuring Product Stability–Choosing the Right Excipients
The stability of pharmaceuticals is an important product quality attribute. Of the known factors
affecting stability, moisture is often perceived as the most common cause of drug …
affecting stability, moisture is often perceived as the most common cause of drug …
Compatibility study between lipoic acid with polymers used in controlled drug release systems
PCD Silva, AS Portela, RSC Lima, CP Santana… - Journal of Thermal …, 2016 - Springer
Lipoic acid is derived from octanoic acid and is considered a universal antioxidant for
combating free radicals and regeneration of endogenous antioxidant, as well as acting like …
combating free radicals and regeneration of endogenous antioxidant, as well as acting like …
[HTML][HTML] Drug-excipient compatibility study through a novel vial-in-vial experimental setup: a benchmark study
S Jain, RP Shah - AAPS pharmscitech, 2023 - Springer
Drug-excipient compatibility study (DECS) is one of the critical steps during pre-formulation
studies to select the appropriate excipient to obtain a stable formulation/dosage form. As …
studies to select the appropriate excipient to obtain a stable formulation/dosage form. As …
Preformulation: The use of FTIR in compatibility studies
AI Segall - 2019 - notablesdelaciencia.conicet.gov.ar
Studies of active pharmaceutical ingredient (API)-excipient compatibility represent an
important study in the preformulation stage of the development of new dosage forms. The …
important study in the preformulation stage of the development of new dosage forms. The …
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