Glioblastoma is the most common malignant primary brain tumor. Overall, the prognosis for
patients with this disease is poor, with a median survival of< 2 years. There is a slight …

Faced with unique immunobiology and marked heterogeneity, treatment strategies for
glioblastoma require therapeutic approaches that diverge from conventional oncological …

Importance Glioblastoma is the most common primary malignant brain tumor, but despite
multimodal treatment with surgery, radiotherapy, and temozolomide chemotherapy, the …

Glioblastomas are the most common malignant brain tumor and despite extensive research
have a dismal prognosis. This review focuses on the current treatment paradigms of …

Background: Glioblastoma multiforme is a malignant intracranial neoplasm that constitutes a
therapeutic challenge because of the associated high morbidity and mortality given the lack …

Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an
extremely poor prognosis. Given the poor survival with currently approved treatments for …

Highlights•As of July 2018, there were 759 ongoing or projected clinical trials for
glioblastoma.•Drug therapies appear compromised by the need to combat tumour …

Glioblastoma is the most common and aggressive primary brain tumor in the adult
population and leads to considerable morbidity and mortality. It has a dismal prognosis with …

Glioblastoma multiforme (GBM) is a primary malignant brain tumor characterized by a high
grade of malignancy and an extremely unfavorable prognosis. The current efficacy of …

This is an exciting time in neuro-oncology. Discoveries elucidating the molecular
mechanisms of oncogenesis and the molecular subtypes of glioblastoma multiforme (GBM) …