[HTML][HTML] Current and emerging therapeutic approaches to pulmonary hypertension

M Bisserier, N Pradhan, L Hadri - Reviews in cardiovascular …, 2020 - ncbi.nlm.nih.gov
Pulmonary arterial hypertension (PAH) is a progressive and fatal lung disease of
multifactorial etiology. Most of the available drugs and FDA-approved therapies for treating …

Evidence-based pharmacologic management of pulmonary arterial hypertension

N Benedict, A Seybert, MA Mathier - Clinical therapeutics, 2007 - Elsevier
Background: Pulmonary arterial hypertension (PAH) is a debilitating chronic disorder of the
pulmonary vasculature characterized by elevated mean pulmonary arterial pressure, right …

[HTML][HTML] Recent advances in the treatment of pulmonary arterial hypertension

N Otani, T Tomoe, A Kawabe, T Sugiyama, Y Horie… - Pharmaceuticals, 2022 - mdpi.com
Pulmonary arterial hypertension (PAH) is a disease in which stenosis or obstruction of the
pulmonary arteries (PAs) causes an increase in PA pressure, leading to right-sided heart …

The pharmacological treatment of pulmonary arterial hypertension

LR Frumkin - Pharmacological reviews, 2012 - ASPET
Pulmonary arterial hypertension (PAH) is a life-threatening and progressive disease of
various origins characterized by pulmonary vascular remodeling that leads to increased …

Steps forward in the treatment of pulmonary arterial hypertension: latest developments and clinical opportunities

JB Badlam, TM Bull - Therapeutic advances in chronic …, 2017 - journals.sagepub.com
Pulmonary arterial hypertension (PAH) is a chronic disease that results in narrowing of the
small pre-capillary pulmonary arteries leading to elevation of pulmonary artery pressure and …

[HTML][HTML] Management of pulmonary arterial hypertension

JD Mayeux, IZ Pan, J Dechand, JA Jacobs… - Current cardiovascular …, 2021 - Springer
Abstract Purpose of Review This review focuses on the therapeutic management and
individualized approach to Group 1 pulmonary arterial hypertension (PAH), utilizing Food …

Therapeutic advances in pulmonary arterial hypertension

K Boutet, D Montani, X Jaïs, A Yaïci… - Therapeutic …, 2008 - journals.sagepub.com
Pulmonary arterial hypertension (PAH) is characterized by vasoconstriction, in situ
thrombosis, and vascular remodeling of small pulmonary arteries inducing increased …

Current therapeutics and practical management strategies for pulmonary arterial hypertension

R Agarwal, M Gomberg-Maitland - American heart journal, 2011 - Elsevier
Pulmonary arterial hypertension (PAH) develops from an abnormal interaction between the
endothelium and smooth muscle cells in the pulmonary vasculature and is characterized by …

[HTML][HTML] Pulmonary arterial hypertension: pathophysiology and treatment

NSH Lan, BD Massam, SS Kulkarni, CC Lang - Diseases, 2018 - mdpi.com
Pulmonary arterial hypertension (PAH), the first category of pulmonary hypertension, is a
chronic and progressive disorder characterised by angioproliferative vasculopathy in the …

New horizons in pulmonary arterial hypertension therapies

N Galiè, AH Ghofrani - European Respiratory Review, 2013 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a fatal disease associated with vasoconstriction
and vascular remodelling. There are three well-known pathways that contribute to the …