Vitamin D (VitD) is a prohormone most noted for the regulation of calcium and phosphate
levels in circulation, and thus of bone metabolism. Inflammatory and immune cells not only …

Calcitriol, or 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) is a well-known endocrine regulator
of calcium homeostasis. More recently, local calcitriol production by immune cells was …

Abstract vitamin D is a neuro-hormone regulating calcium-phosphate homeostasis, cell
proliferation, and immunomodulation. exogenous and endogenous vitamin D is inactive …

Evidence of the role of vitamin D in the regulation of T and B cells, macrophages, dendritic
cells, and keratinocytes continues to accumulate and provides a link between vitamin D and …

Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis.
Experimental studies have shown that 1, 25-dihydroxyvitamin D (calcitriol) generates …

Accumulating data support that vitamin D possesses several biological and molecular
actions apart from its role in calcium homeostasis. Immune cells express vitamin D receptor …

Vitamin D (VitD) is a hormone primarily synthesized in human skin under the stimulation of
ultraviolet radiation. Beyond its endocrine role in bone metabolism, VitD is endowed with …

Vitamin D is a pleiotropic secosteroid yielding multiple actions in human physiology.
Besides the canonical regulatory activity on bone metabolism, several non-classical actions …

Epidemiological studies have shown that a poor vitamin D status is associated with an
increased risk of several diseases, including autoimmune diseases. The immune regulatory …

Vitamin D has been reported to influence physiological systems that extend far beyond its
established functions in calcium and bone homeostasis. Prominent amongst these are the …