Polychlorinated biphenyl-77 induces adipocyte differentiation and proinflammatory adipokines and promotes obesity and atherosclerosis

V Arsenescu, RI Arsenescu, V King… - Environmental …, 2008 - ehp.niehs.nih.gov
Background Obesity, an inflammatory condition linked to cardiovascular disease, is
associated with expansion of adipose tissue. Highly prevalent coplanar polychlorinated …

Polychlorinated biphenyl 153 is a diet-dependent obesogen that worsens nonalcoholic fatty liver disease in male C57BL6/J mice

B Wahlang, KC Falkner, B Gregory, D Ansert… - The Journal of nutritional …, 2013 - Elsevier
Abstract Background Polychlorinated biphenyls (PCBs) are persistent environmental
pollutants that are detectable in the serum of all American adults. Amongst PCB congeners …

Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese …

NA Baker, M Karounos, V English, J Fang… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs)
promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and …

Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor

B Hennig, G Reiterer, M Toborek… - Environmental …, 2005 - ehp.niehs.nih.gov
There is evidence that dietary fat can modify the cytotoxicity of polychlorinated biphenyls
(PCBs) and that coplanar PCBs can induce inflammatory processes critical in the pathology …

Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture

B Wahlang, KC Falkner, HB Clair… - Toxicological …, 2014 - academic.oup.com
Polychlorinated biphenyls (PCBs) are persistent environmental toxicants, present in 100% of
US adults and dose-dependently associated with obesity and non-alcoholic fatty liver …

PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats

GS Gadupudi, WD Klaren, AK Olivier… - Toxicological …, 2016 - academic.oup.com
Abstract 3, 3′, 4, 4′, 5-Pentachlorobiphenyl (PCB126), a dioxin-like polychlorinated
biphenyl (PCB) and a potent aryl hydrocarbon receptor (AhR) agonist, is implicated in the …

Low-dose bisphenol-A impairs adipogenesis and generates dysfunctional 3T3-L1 adipocytes

F Ariemma, V D'Esposito, D Liguoro, F Oriente… - PloS one, 2016 - journals.plos.org
Environmental endocrine disruptors (EDCs), including bisphenol-A (BPA), have been
recently involved in obesity and diabetes by dysregulating adipose tissue function. Our aim …

[HTML][HTML] Polychlorinated biphenyls-153 induces metabolic dysfunction through activation of ROS/NF-κB signaling via downregulation of HNF1b

H Wu, W Yu, F Meng, J Mi, J Peng, J Liu, X Zhang… - Redox biology, 2017 - Elsevier
Polychlorinated biphenyls (PCB) is a major type of persistent organic pollutants (POPs) that
act as endocrine-disrupting chemicals. In the current study, we examined the mechanism …

Evaluation of Aroclor 1260 exposure in a mouse model of diet-induced obesity and non-alcoholic fatty liver disease

B Wahlang, M Song, JI Beier, KC Falkner… - Toxicology and applied …, 2014 - Elsevier
Polychlorinated biphenyls (PCBs) are persistent organic pollutants associated with non-
alcoholic fatty liver disease (NAFLD) in epidemiologic studies. The purpose of this study was …

Impaired lipid and glucose homeostasis in hexabromocyclododecane-exposed mice fed a high-fat diet

R Yanagisawa, E Koike, TT Win-Shwe… - Environmental …, 2014 - ehp.niehs.nih.gov
Background: Hexabromocyclododecane (HBCD) is an additive flame retardant used in the
textile industry and in polystyrene foam manufacturing. Because of its lipophilicity and …