The novel Hha/YmoA family of nucleoid‐associated proteins: use of structural mimicry to modulate the activity of the H‐NS family of proteins

C Madrid, C Balsalobre, J García… - Molecular …, 2007 - Wiley Online Library
Summary The Hha/YmoA family of proteins is a group of conserved, low‐molecular‐weight
proteins involved in the regulation of gene expression. Studies performed in Escherichia …

Repression of Intracellular Virulence Factors in Salmonella by the Hha and YdgT Nucleoid-Associated Proteins

U Silphaduang, M Mascarenhas, M Karmali… - Journal of …, 2007 - Am Soc Microbiol
ABSTRACT The Hha/YmoA family of nucleoid-associated proteins is involved in gene
regulation in enterobacteria. In Salmonella enterica serovar Typhimurium, virulence genes …

Horizontally acquired homologues of the nucleoid‐associated protein H‐NS: implications for gene regulation

CJ Dorman - Molecular microbiology, 2010 - Wiley Online Library
H‐NS is one of the most intensively studied members of the family of bacterial nucleoid‐
associated proteins. It is a DNA‐binding protein with a preference for A+ T‐rich DNA …

Molecular aspects of the E. coli nucleoid protein, H-NS: a central controller of gene regulatory networks

RM Williams, S Rimsky - FEMS microbiology letters, 1997 - academic.oup.com
The nucleoid-associated protein H-NS has a central role in the structuring and control of the
enteric bacterial chromosome. This protein has been demonstrated to contribute to the …

Evidence for direct protein-protein interaction between members of the enterobacterial Hha/YmoA and H-NS families of proteins

JM Nieto, C Madrid, E Miquelay, JL Parra… - Journal of …, 2002 - Am Soc Microbiol
Escherichia coli nucleoid-associated H-NS protein interacts with the Hha protein, a member
of a new family of global modulators that also includes the YmoA protein from Yersinia …

Interaction between the bacterial nucleoid associated proteins Hha and H-NS involves a conformational change of Hha

J García, TN Cordeiro, JM Nieto, I Pons… - Biochemical …, 2005 - portlandpress.com
The H-NS family of proteins has been shown to participate in the regulation of a large
number of genes in Gram-negative bacteria in response to environmental factors. In recent …

Large‐scale monitoring of pleiotropic regulation of gene expression by the prokaryotic nucleoid‐associated protein, H‐NS

F Hommais, E Krin, C Laurent‐Winter… - Molecular …, 2001 - Wiley Online Library
Despite many years of intense work investigating the function of nucleoid‐associated
proteins in prokaryotes, their role in bacterial physiology remains largely unknown. The two …

Clarification of the dimerization domain and its functional significance for the Escherichia coli nucleoid protein H-NS

C Ueguchi, C Seto, T Suzuki, T Mizuno - Journal of molecular biology, 1997 - Elsevier
The Escherichia coli nucleoid protein, H-NS, functions as a global regulator for expression of
a wide variety of genes. We recently analyzed the structure-function relationship of H-NS …

Systematic Mutational Analysis Revealing the Functional Domain Organization ofEscherichia coliNucleoid Protein H-NS

C Ueguchi, T Suzuki, T Yoshida, K Tanaka… - Journal of molecular …, 1996 - Elsevier
TheEscherichia coliH-NS protein is one of the major constituents of the nucleoid structure.
This protein has been implicated not only in the compact organization of the nucleoid …

Synthesis of the Escherichia coli K‐12 nucleoid‐associated DNA‐binding protein H‐NS is subjected to growth‐phase control and autoregulation

P Dersch, K Schmidt, E Bremer - Molecular microbiology, 1993 - Wiley Online Library
Mutations in the structural gene (hns) for the Escherichia coli nucleoid‐associated DNA‐
binding protein H‐NS cause highly pleiotropic effects on gene expression, site‐specific …