The identification of proteins as new cancer diagnostic and prognostic biomarkers continues
to attract considerable attention in the oncology literature, especially in the context of …

Some phenotypical traits, for example, chemoresistance and metastasis, are likely regulated
by a fine-tuned balance between several metabolic processes and events that are …

The idea that mitochondrial functions correlate with tumor malignancy recently arose
together with the indication that respiration and processing of different nutrients, as well as …

Mitochondria and energy metabolism 3. Metabolic remodelling in cancer cells 4. Metabolic
signaling in cancer cells 5. Origin of cancer cells' metabolic reprogramming 6. Mitochondrial …

Abstract Mitochondrial DNA (mtDNA), encoding 13 out of more than 1,000 proteins of the
mitochondrial proteome, is of paramount importance for the bioenergetic machinery of …

Cancers are often affected by derangements in mitochondrial (mt) function, as well as
mtDNA mutations. In this issue, Tan et al.(2015) demonstrate that only mtDNA-depleted …

The primacy of glucose derived from photosynthesis as an existential source of chemical
energy across plant and animal phyla is universally accepted as a core principle in the …

Although mitochondrial respiration is decreased in most cancer cells, the role of this
decrease in carcinogenesis and cancer progression is still unclear. To better understand this …

Mitochondria have an essential role in powering cells by generating ATP following the
metabolism of pyruvate derived from glycolysis. They are also the major source of …

Decades ago, Otto Warburg observed that cancers ferment glucose in the presence of
oxygen, suggesting that defects in mitochondrial respiration may be the underlying cause of …