D-ribose-mediated glycation of fibrinogen: role in the induction of adaptive immune response
A nonenzymatic reaction between reducing sugars and amino groups of proteins results in
the formation of advanced glycation end products, which are linked to a number of chronic …
the formation of advanced glycation end products, which are linked to a number of chronic …
Methylglyoxal mediated glycation leads to neo-epitopes generation in fibrinogen: Role in the induction of adaptive immune response
In diabetes mellitus, hyperglycemia mediated non-enzymatic glycosylation of proteins
results in the pathogenesis of diabetes-associated secondary complications via the …
results in the pathogenesis of diabetes-associated secondary complications via the …
Generation of autoantibodies against glycated fibrinogen: Role in diabetic nephropathy and retinopathy
The process of glycation, characterized by the non-enzymatic reaction between sugars and
free amino groups on biomolecules, is a key contributor to the development and progression …
free amino groups on biomolecules, is a key contributor to the development and progression …
Glycation of hemoglobin leads to the immunogenicity as a result of neo-epitope generation
Non-enzymatic glycation occurs rapidly which ultimately leads to the formation of advanced
glycation endproducts (AGEs). These AGEs have shown to associated with the development …
glycation endproducts (AGEs). These AGEs have shown to associated with the development …
Acquired immunogenicity of calf thymus DNA and LDL modified by D-ribose: a comparative study
Glycation of biologically important macromolecules leads to the establishment of advanced
glycation end products (AGEs) having significant role in the pathophysiology of various …
glycation end products (AGEs) having significant role in the pathophysiology of various …
The neoepitopes on methylglyoxal‐(MG‐) glycated fibrinogen generate autoimmune response: its role in diabetes, atherosclerosis, and diabetic atherosclerosis …
Objectives. In diabetes mellitus, hyperglycemia‐mediated nonenzymatic glycosylation of
fibrinogen protein plays a crucial role in the pathogenesis of micro‐and macrovascular …
fibrinogen protein plays a crucial role in the pathogenesis of micro‐and macrovascular …
Reactive immunization suppresses advanced glycation and mitigates diabetic nephropathy
T Shcheglova, S Makker… - Journal of the American …, 2009 - journals.lww.com
Agents that inhibit glycation end products by reducing the carbonyl load from glycation and
glycoxidation are an emerging pharmacologic approach to treat complications of diabetes …
glycoxidation are an emerging pharmacologic approach to treat complications of diabetes …
Influence of arginine deimination on antigenicity of fibrinogen
S Hida, NN Miura, Y Adachi, N Ohno - Journal of autoimmunity, 2004 - Elsevier
Autoreactivity is controlled at various steps by numerous mechanisms and is a key to
understanding and treating autoimmune disease. Recently, an antibody against deiminated …
understanding and treating autoimmune disease. Recently, an antibody against deiminated …
Nonenzymatic glycosylation of isolated human immunoglobulin‐G by D‐ribose
S Ahmad, K Al‐Shaghdali, S Rehman… - Cell Biochemistry …, 2022 - Wiley Online Library
Glycation is vital in terms of its damaging effect on macromolecules resulting in the formation
of end products, which are highly reactive and cross‐linked irreversible structures, known as …
of end products, which are highly reactive and cross‐linked irreversible structures, known as …
Antigenic role of the adaptive immune response to d-ribose glycated LDL in diabetes, atherosclerosis and diabetes atherosclerotic patients
Aims Glycation of proteins leads to the formation of advanced glycation end products (AGEs,
which have significant role in the pathophysiology of diabetes complications. d-ribose …
which have significant role in the pathophysiology of diabetes complications. d-ribose …