Main role of antibodies in demyelination and axonal damage in Multiple Sclerosis
Ú Muñoz Morón, C Sebal… - Cellular and … - repositorioinstitucional.ceu.es
Antibodies and oxidative stress are hallmarks of multiple sclerosis (MS) lesions. We aimed
to clarify the relation between them, their role in MS patients and to investigate their …
to clarify the relation between them, their role in MS patients and to investigate their …
Main role of antibodies in demyelination and axonal damage in multiple sclerosis
U Muñoz, C Sebal, E Escudero, M Esiri… - Cellular and Molecular …, 2022 - Springer
Antibodies and oxidative stress are hallmarks of multiple sclerosis (MS) lesions. We aimed
to clarify the relation between them, their role in MS patients and to investigate their …
to clarify the relation between them, their role in MS patients and to investigate their …
Axonal and oligodendrocyte-localized IgM and IgG deposits in MS lesions
BACKGROUND: Recent findings support the important role of antibodies in multiple
sclerosis (MS) physiopathology. Thus, local IgG synthesis is a hallmark of the disease, and …
sclerosis (MS) physiopathology. Thus, local IgG synthesis is a hallmark of the disease, and …
Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: implications for multiple sclerosis
Axonal damage is a correlate for increasing disability in multiple sclerosis. Animal models
such as experimental autoimmune encephalomyelitis (EAE) may help to develop better …
such as experimental autoimmune encephalomyelitis (EAE) may help to develop better …
An update on multiple sclerosis
SL Hauser - Journal of the neurological sciences, 2005 - jns-journal.com
Multiple sclerosis (MS) is the prototypic inflammatory demyelinating disorder of the central
nervous system (CNS). MS is a clinically heterogeneous entity; symptoms may manifest in a …
nervous system (CNS). MS is a clinically heterogeneous entity; symptoms may manifest in a …
Transient axonal injury in the absence of demyelination: a correlate of clinical disease in acute experimental autoimmune encephalomyelitis
F Aboul-Enein, P Weiser, R Höftberger… - Acta …, 2006 - Springer
Axonal degeneration contributes to the transient and permanent neurological deficits seen
in multiple sclerosis, an inflammatory disease of the central nervous system. To study the …
in multiple sclerosis, an inflammatory disease of the central nervous system. To study the …
[HTML][HTML] Serum anti-oligodendrocyte autoantibodies in patients with multiple sclerosis detected by a tissue-based immunofluorescence assay
Y Miyachi, T Fujii, R Yamasaki, D Tsuchimoto… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS), the most prevalent inflammatory disease of the central nervous
system (CNS), is characterized by damaged to myelin sheaths and oligodendrocytes …
system (CNS), is characterized by damaged to myelin sheaths and oligodendrocytes …
[HTML][HTML] Autoantibodies and neurodegeneration in multiple sclerosis
T Vyshkina, B Kalman - Laboratory investigation, 2008 - Elsevier
Neurodegeneration develops in association with inflammation and demyelination in multiple
sclerosis. Available data suggest that the progressive neuroaxonal loss begins in the …
sclerosis. Available data suggest that the progressive neuroaxonal loss begins in the …
Innate and adaptive immunity in amyotrophic lateral sclerosis: evidence of complement activation
M Sta, RMR Sylva-Steenland, M Casula… - Neurobiology of …, 2011 - Elsevier
Increasing evidence suggests a role for the immune system in amyotrophic lateral sclerosis
(ALS). To determine the extent of the immune activation in ALS we analyzed the expression …
(ALS). To determine the extent of the immune activation in ALS we analyzed the expression …
Oxidative stress is differentially present in multiple sclerosis courses, early evident, and unrelated to treatment
M Gironi, B Borgiani, E Mariani… - Journal of …, 2014 - Wiley Online Library
Background. Oxidative stress is well documented in multiple sclerosis (MS) lesions, but its
correspondence at peripheral level is still controversial. Objective. To evaluate peripheral …
correspondence at peripheral level is still controversial. Objective. To evaluate peripheral …